Bonni A - Search Results

1

PHF6-mediated transcriptional control of NSC via Ephrin receptors is impaired in the intellectual disability syndrome BFLS.

Rasool D, Burban A, Sharanek A, Madrigal A, Hu J, Yan K, Qu D, Voss AK, Slack RS, Thomas T, Bonni A, Picketts DJ, Soleimani VD, Najafabadi HS, Jahani-Asl A. Rasool D, et al. Among authors: bonni a. EMBO Rep. 2024 Mar;25(3):1256-1281. doi: 10.1038/s44319-024-00082-0. Epub 2024 Mar 1. EMBO Rep. 2024. PMID: 38429579 Free PMC article.

2

MeCP2 represses the activity of topoisomerase IIβ in long neuronal genes.

Nettles SA, Ikeuchi Y, Lefton KB, Abbasi L, Erickson A, Agwu C, Papouin T, Bonni A, Gabel HW. Nettles SA, et al. Among authors: bonni a. Cell Rep. 2023 Dec 26;42(12):113538. doi: 10.1016/j.celrep.2023.113538. Epub 2023 Dec 12. Cell Rep. 2023. PMID: 38096051 Free PMC article.

3

Sustained effect of prasinezumab on Parkinson's disease motor progression in the open-label extension of the PASADENA trial.

Pagano G, Monnet A, Reyes A, Ribba B, Svoboda H, Kustermann T, Simuni T, Postuma RB, Pavese N, Stocchi F, Brockmann K, Smigorski K, Gerbaldo V, Fontoura P, Doody R, Kerchner GA, Brundin P, Marek K, Bonni A, Nikolcheva T; PASADENA Investigators; Prasinezumab Study Group. Pagano G, et al. Among authors: bonni a. Nat Med. 2024 Oct 8. doi: 10.1038/s41591-024-03270-6. Online ahead of print. Nat Med. 2024. PMID: 39379705

4

Prasinezumab slows motor progression in rapidly progressing early-stage Parkinson's disease.

Pagano G, Taylor KI, Anzures Cabrera J, Simuni T, Marek K, Postuma RB, Pavese N, Stocchi F, Brockmann K, Svoboda H, Trundell D, Monnet A, Doody R, Fontoura P, Kerchner GA, Brundin P, Nikolcheva T, Bonni A; PASADENA Investigators; Prasinezumab Study Group. Pagano G, et al. Among authors: bonni a. Nat Med. 2024 Apr;30(4):1096-1103. doi: 10.1038/s41591-024-02886-y. Epub 2024 Apr 15. Nat Med. 2024. PMID: 38622249 Free PMC article.

5

Targeted ASO-mediated Atp1a2 knockdown in astrocytes reduces SOD1 aggregation and accelerates disease onset in mutant SOD1 mice.

Iyer AK, Schoch KM, Verbeck A, Galasso G, Chen H, Smith S, Oldenborg A, Miller TM, Karch CM, Bonni A. Iyer AK, et al. Among authors: bonni a. PLoS One. 2023 Nov 28;18(11):e0294731. doi: 10.1371/journal.pone.0294731. eCollection 2023. PLoS One. 2023. PMID: 38015828 Free PMC article.

6

The Hao-Fountain syndrome protein USP7 regulates neuronal connectivity in the brain via a novel p53-independent ubiquitin signaling pathway.

Chen H, Ferguson CJ, Mitchell DC, Titus A, Paulo JA, Hwang A, Lin TH, Yano H, Gu W, Song SK, Yuede CM, Gygi SP, Bonni A, Kim AH. Chen H, et al. Among authors: bonni a. bioRxiv [Preprint]. 2024 Jun 29:2023.10.24.563880. doi: 10.1101/2023.10.24.563880. bioRxiv. 2024. PMID: 37961719 Free PMC article. Preprint.

7

The anaphase-promoting complex controls a ubiquitination-phosphoprotein axis in chromatin during neurodevelopment.

Ledvin L, Gassaway BM, Tawil J, Urso O, Pizzo D, Welsh KA, Bolhuis DL, Fisher D, Bonni A, Gygi SP, Brown NG, Ferguson CJ. Ledvin L, et al. Among authors: bonni a. Dev Cell. 2023 Dec 4;58(23):2666-2683.e9. doi: 10.1016/j.devcel.2023.10.002. Epub 2023 Oct 23. Dev Cell. 2023. PMID: 37875116 Free article.

8

Sumoylated SnoN interacts with HDAC1 and p300/CBP to regulate EMT-associated phenotypes in mammary organoids.

Chanda A, Sarkar A, Deng L, Bonni A, Bonni S. Chanda A, et al. Among authors: bonni a. Cell Death Dis. 2023 Jul 7;14(7):405. doi: 10.1038/s41419-023-05921-x. Cell Death Dis. 2023. PMID: 37414747 Free PMC article.

9

Increased G3BP2-Tau interaction in tauopathies is a natural defense against Tau aggregation.

Wang C, Terrigno M, Li J, Distler T, Pandya NJ, Ebeling M, Tyanova S, Hoozemans JJM, Dijkstra AA, Fuchs L, Xiang S, Bonni A, Grüninger F, Jagasia R. Wang C, et al. Among authors: bonni a. Neuron. 2023 Sep 6;111(17):2660-2674.e9. doi: 10.1016/j.neuron.2023.05.033. Epub 2023 Jun 28. Neuron. 2023. PMID: 37385246 Free article.

10

This is NOT the End for Immunotherapy in Parkinson's Disease - A Perspective from Early Drug Development Scientists.

Brundin P, Svoboda H, Bonni A, Pagano G. Brundin P, et al. Among authors: bonni a. J Parkinsons Dis. 2022;12(8):2293-2296. doi: 10.3233/JPD-229008. J Parkinsons Dis. 2022. PMID: 36404558 No abstract available.

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