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The hydrophilic extract from a new tomato genotype (named DHO) kills cancer cell lines through the modulation of the DNA damage response induced by Campthotecin treatment.
Barone D, Iannuzzi CA, Forte IM, Ragosta MC, Cuomo M, Dell'Aquila M, Altieri A, Caporaso A, Camerlingo R, Rigano MM, Monti DM, Barone A, Imbimbo P, Frusciante L, Monda M, D'Angelo M, De Laurentiis M, Giordano A, Alfano L. Barone D, et al. Among authors: ragosta mc. Front Oncol. 2023 Jun 20;13:1117262. doi: 10.3389/fonc.2023.1117262. eCollection 2023. Front Oncol. 2023. PMID: 37409248 Free PMC article.
Oleanolic Acid Modulates DNA Damage Response to Camptothecin Increasing Cancer Cell Death.
Mazzarotti G, Cuomo M, Ragosta MC, Russo A, D'Angelo M, Medugno A, Napolitano GM, Iannuzzi CA, Forte IM, Camerlingo R, Burk S, Errichiello F, Frusciante L, Forino M, Campitiello MR, De Laurentiis M, Giordano A, Alfano L. Mazzarotti G, et al. Among authors: ragosta mc. Int J Mol Sci. 2024 Dec 16;25(24):13475. doi: 10.3390/ijms252413475. Int J Mol Sci. 2024. PMID: 39769237 Free PMC article.