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Activity of the Ubiquitin-activating Enzyme Inhibitor TAK-243 in Adrenocortical Carcinoma Cell Lines, Patient-derived Organoids, and Murine Xenografts.
Arakawa Y, Jo U, Kumar S, Sun NY, Elloumi F, Thomas A, Roper N, Varghese DG, Takebe N, Zhang X, Ceribelli M, Holland DO, Beck E, Itkin Z, McKnight C, Wilson KM, Travers J, Klumpp-Thomas C, Thomas CJ, Hoang CD, Hernandez JM, Del Rivero J, Pommier Y. Arakawa Y, et al. Among authors: thomas a, thomas cj. Cancer Res Commun. 2024 Mar 19;4(3):834-848. doi: 10.1158/2767-9764.CRC-24-0085. Cancer Res Commun. 2024. PMID: 38451783 Free PMC article.
Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma.
Yang Y, Shaffer AL 3rd, Emre NC, Ceribelli M, Zhang M, Wright G, Xiao W, Powell J, Platig J, Kohlhammer H, Young RM, Zhao H, Yang Y, Xu W, Buggy JJ, Balasubramanian S, Mathews LA, Shinn P, Guha R, Ferrer M, Thomas C, Waldmann TA, Staudt LM. Yang Y, et al. Cancer Cell. 2012 Jun 12;21(6):723-37. doi: 10.1016/j.ccr.2012.05.024. Cancer Cell. 2012. PMID: 22698399 Free PMC article.
Multiplexing high-content flow (HCF) and quantitative high-throughput screening (qHTS) to identify compounds capable of decreasing cell viability, activating caspase 3/7, expressing annexin V, and changing mitochondrial membrane integrity.
Mathews LA, Keller JM, McKnight C, Michael S, Shinn P, Liu D, Staudt LM, Thomas CJ, Ferrer M. Mathews LA, et al. Among authors: thomas cj. Curr Protoc Chem Biol. 2013;5(3):195-212. doi: 10.1002/9780470559277.ch130060. Curr Protoc Chem Biol. 2013. PMID: 24391083
Blockade of oncogenic IκB kinase activity in diffuse large B-cell lymphoma by bromodomain and extraterminal domain protein inhibitors.
Ceribelli M, Kelly PN, Shaffer AL, Wright GW, Xiao W, Yang Y, Mathews Griner LA, Guha R, Shinn P, Keller JM, Liu D, Patel PR, Ferrer M, Joshi S, Nerle S, Sandy P, Normant E, Thomas CJ, Staudt LM. Ceribelli M, et al. Among authors: thomas cj. Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11365-70. doi: 10.1073/pnas.1411701111. Epub 2014 Jul 21. Proc Natl Acad Sci U S A. 2014. PMID: 25049379 Free PMC article.
High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations.
Mott BT, Eastman RT, Guha R, Sherlach KS, Siriwardana A, Shinn P, McKnight C, Michael S, Lacerda-Queiroz N, Patel PR, Khine P, Sun H, Kasbekar M, Aghdam N, Fontaine SD, Liu D, Mierzwa T, Mathews-Griner LA, Ferrer M, Renslo AR, Inglese J, Yuan J, Roepe PD, Su XZ, Thomas CJ. Mott BT, et al. Among authors: thomas cj. Sci Rep. 2015 Sep 25;5:13891. doi: 10.1038/srep13891. Sci Rep. 2015. PMID: 26403635 Free PMC article.
RNA Polymerase II Regulates Topoisomerase 1 Activity to Favor Efficient Transcription.
Baranello L, Wojtowicz D, Cui K, Devaiah BN, Chung HJ, Chan-Salis KY, Guha R, Wilson K, Zhang X, Zhang H, Piotrowski J, Thomas CJ, Singer DS, Pugh BF, Pommier Y, Przytycka TM, Kouzine F, Lewis BA, Zhao K, Levens D. Baranello L, et al. Among authors: thomas cj. Cell. 2016 Apr 7;165(2):357-71. doi: 10.1016/j.cell.2016.02.036. Cell. 2016. PMID: 27058666 Free PMC article.
547 results