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MX2 forms nucleoporin-comprising cytoplasmic biomolecular condensates that lure viral capsids.
Moschonas GD, Delhaye L, Cooreman R, Hüsers F, Bhat A, Stylianidou Z, De Bousser E, De Pryck L, Grzesik H, De Sutter D, Parthoens E, De Smet AS, Maciejczuk A, Lippens S, Callewaert N, Vandekerckhove L, Debyser Z, Sodeik B, Eyckerman S, Saelens X. Moschonas GD, et al. Among authors: debyser z. Cell Host Microbe. 2024 Oct 9;32(10):1705-1724.e14. doi: 10.1016/j.chom.2024.09.002. Cell Host Microbe. 2024. PMID: 39389033 Free article.
Prime editing functionally corrects cystic fibrosis-causing CFTR mutations in human organoids and airway epithelial cells.
Bulcaen M, Kortleven P, Liu RB, Maule G, Dreano E, Kelly M, Ensinck MM, Thierie S, Smits M, Ciciani M, Hatton A, Chevalier B, Ramalho AS, Casadevall I Solvas X, Debyser Z, Vermeulen F, Gijsbers R, Sermet-Gaudelus I, Cereseto A, Carlon MS. Bulcaen M, et al. Among authors: debyser z. Cell Rep Med. 2024 May 21;5(5):101544. doi: 10.1016/j.xcrm.2024.101544. Epub 2024 May 1. Cell Rep Med. 2024. PMID: 38697102 Free PMC article.
A dual role for PSIP1/LEDGF in T cell acute lymphoblastic leukemia.
Demoen L, Matthijssens F, Reunes L, Palhais B, Lintermans B, T'Sas S, Fijalkowski I, Taminau J, Akele MZ, Van Belle S, Taghon T, Deforce D, Van Nieuwerburgh F, Berx G, Ntziachristos P, Debyser Z, Durinck K, Pieters T, Goossens S, Van Vlierberghe P. Demoen L, et al. Among authors: debyser z. Sci Adv. 2024 Nov;10(44):eado6765. doi: 10.1126/sciadv.ado6765. Epub 2024 Nov 1. Sci Adv. 2024. PMID: 39485844 Free PMC article.
Rational fragment-based design of compounds targeting the PWWP domain of the HRP family.
Vantieghem T, Aslam NA, Osipov EM, Akele M, Van Belle S, Beelen S, Drexler M, Paulovcakova T, Lux V, Fearon D, Douangamath A, von Delft F, Christ F, Veverka V, Verwilst P, Van Aerschot A, Debyser Z, Strelkov SV. Vantieghem T, et al. Among authors: debyser z. Eur J Med Chem. 2024 Dec 15;280:116960. doi: 10.1016/j.ejmech.2024.116960. Epub 2024 Oct 11. Eur J Med Chem. 2024. PMID: 39461037
325 results