Lees-Miller SP - Search Results

1

Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology.

Filandr F, Sarpe V, Raval S, Crowder DA, Khan MF, Douglas P, Coales S, Viner R, Syed A, Tainer JA, Lees-Miller SP, Schriemer DC. Filandr F, et al. Among authors: lees miller sp. Nat Commun. 2024 Mar 11;15(1):2200. doi: 10.1038/s41467-024-46610-3. Nat Commun. 2024. PMID: 38467655 Free PMC article.

2

Protein phosphatases regulate DNA-dependent protein kinase activity.

Douglas P, Moorhead GB, Ye R, Lees-Miller SP. Douglas P, et al. J Biol Chem. 2001 Jun 1;276(22):18992-8. doi: 10.1074/jbc.M011703200. Epub 2001 Mar 16. J Biol Chem. 2001. PMID: 11376007 Free article.

3

Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase.

Douglas P, Sapkota GP, Morrice N, Yu Y, Goodarzi AA, Merkle D, Meek K, Alessi DR, Lees-Miller SP. Douglas P, et al. Biochem J. 2002 Nov 15;368(Pt 1):243-51. doi: 10.1042/BJ20020973. Biochem J. 2002. PMID: 12186630 Free PMC article.

4

The DNA-dependent protein kinase interacts with DNA to form a protein-DNA complex that is disrupted by phosphorylation.

Merkle D, Douglas P, Moorhead GB, Leonenko Z, Yu Y, Cramb D, Bazett-Jones DP, Lees-Miller SP. Merkle D, et al. Biochemistry. 2002 Oct 22;41(42):12706-14. doi: 10.1021/bi0263558. Biochemistry. 2002. PMID: 12379113

5

DNA-PK phosphorylation sites in XRCC4 are not required for survival after radiation or for V(D)J recombination.

Yu Y, Wang W, Ding Q, Ye R, Chen D, Merkle D, Schriemer D, Meek K, Lees-Miller SP. Yu Y, et al. DNA Repair (Amst). 2003 Nov 21;2(11):1239-52. doi: 10.1016/s1568-7864(03)00143-5. DNA Repair (Amst). 2003. PMID: 14599745

6

Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species.

Kurz EU, Douglas P, Lees-Miller SP. Kurz EU, et al. J Biol Chem. 2004 Dec 17;279(51):53272-81. doi: 10.1074/jbc.M406879200. Epub 2004 Oct 14. J Biol Chem. 2004. PMID: 15489221 Free article.

7

Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A.

Goodarzi AA, Jonnalagadda JC, Douglas P, Young D, Ye R, Moorhead GB, Lees-Miller SP, Khanna KK. Goodarzi AA, et al. EMBO J. 2004 Nov 10;23(22):4451-61. doi: 10.1038/sj.emboj.7600455. Epub 2004 Oct 28. EMBO J. 2004. PMID: 15510216 Free PMC article.

8

DNA-PK-dependent phosphorylation of Ku70/80 is not required for non-homologous end joining.

Douglas P, Gupta S, Morrice N, Meek K, Lees-Miller SP. Douglas P, et al. DNA Repair (Amst). 2005 Aug 15;4(9):1006-18. doi: 10.1016/j.dnarep.2005.05.003. DNA Repair (Amst). 2005. PMID: 15941674

9

The DNA-dependent protein kinase catalytic subunit is phosphorylated in vivo on threonine 3950, a highly conserved amino acid in the protein kinase domain.

Douglas P, Cui X, Block WD, Yu Y, Gupta S, Ding Q, Ye R, Morrice N, Lees-Miller SP, Meek K. Douglas P, et al. Mol Cell Biol. 2007 Mar;27(5):1581-91. doi: 10.1128/MCB.01962-06. Epub 2006 Dec 11. Mol Cell Biol. 2007. PMID: 17158925 Free PMC article.

10

Utilizing protein phosphatase inhibitors to define PP2A as a regulator of ataxia-telangiectasia mutated.

Goodarzi AA, Douglas P, Moorhead GB, Lees-Miller SP. Goodarzi AA, et al. Methods Mol Biol. 2007;365:47-59. doi: 10.1385/1-59745-267-X:47. Methods Mol Biol. 2007. PMID: 17200553

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