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Person-specific differences in ubiquitin-proteasome mediated proteostasis in human neurons.
Hsieh YC, Augur ZM, Arbery M, Ashour N, Barrett K, Pearse RV 2nd, Tio ES, Duong DM, Felsky D, De Jager PL, Bennett DA, Seyfried NT, Young-Pearse TL. Hsieh YC, et al. Among authors: young pearse tl. Alzheimers Dement. 2024 Apr;20(4):2952-2967. doi: 10.1002/alz.13680. Epub 2024 Mar 12. Alzheimers Dement. 2024. PMID: 38470006 Free PMC article.
Cell-type Dependent Alzheimer's Disease Phenotypes: Probing the Biology of Selective Neuronal Vulnerability.
Muratore CR, Zhou C, Liao M, Fernandez MA, Taylor WM, Lagomarsino VN, Pearse RV 2nd, Rice HC, Negri JM, He A, Srikanth P, Callahan DG, Shin T, Zhou M, Bennett DA, Noggle S, Love JC, Selkoe DJ, Young-Pearse TL. Muratore CR, et al. Stem Cell Reports. 2017 Dec 12;9(6):1868-1884. doi: 10.1016/j.stemcr.2017.10.015. Epub 2017 Nov 16. Stem Cell Reports. 2017. PMID: 29153990 Free PMC article.
A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer's disease.
Mostafavi S, Gaiteri C, Sullivan SE, White CC, Tasaki S, Xu J, Taga M, Klein HU, Patrick E, Komashko V, McCabe C, Smith R, Bradshaw EM, Root DE, Regev A, Yu L, Chibnik LB, Schneider JA, Young-Pearse TL, Bennett DA, De Jager PL. Mostafavi S, et al. Nat Neurosci. 2018 Jun;21(6):811-819. doi: 10.1038/s41593-018-0154-9. Epub 2018 May 25. Nat Neurosci. 2018. PMID: 29802388 Free PMC article.
Targeted brain proteomics uncover multiple pathways to Alzheimer's dementia.
Yu L, Petyuk VA, Gaiteri C, Mostafavi S, Young-Pearse T, Shah RC, Buchman AS, Schneider JA, Piehowski PD, Sontag RL, Fillmore TL, Shi T, Smith RD, De Jager PL, Bennett DA. Yu L, et al. Ann Neurol. 2018 Jul;84(1):78-88. doi: 10.1002/ana.25266. Epub 2018 Jul 3. Ann Neurol. 2018. PMID: 29908079 Free PMC article.
Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer's human brains.
Klein HU, McCabe C, Gjoneska E, Sullivan SE, Kaskow BJ, Tang A, Smith RV, Xu J, Pfenning AR, Bernstein BE, Meissner A, Schneider JA, Mostafavi S, Tsai LH, Young-Pearse TL, Bennett DA, De Jager PL. Klein HU, et al. Nat Neurosci. 2019 Jan;22(1):37-46. doi: 10.1038/s41593-018-0291-1. Epub 2018 Dec 17. Nat Neurosci. 2019. PMID: 30559478 Free PMC article.
Complex Neurological Phenotype in Female Carriers of NHE6 Mutations.
Pescosolido MF, Kavanaugh BC, Pochet N, Schmidt M, Jerskey BA, Rogg JM, De Jager PL, Young-Pearse TL, Liu JS, Morrow EM. Pescosolido MF, et al. Mol Neuropsychiatry. 2019 Apr;5(2):98-108. doi: 10.1159/000496341. Epub 2019 Mar 6. Mol Neuropsychiatry. 2019. PMID: 31192222 Free PMC article.
69 results