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Page 1
An ultra-early, transient interferon-associated innate immune response associates with protection from SARS-CoV-2 infection despite exposure.
Fenn J, Madon K, Conibear E, Derelle R, Nevin S, Kundu R, Hakki S, Tregoning JS, Koycheva A, Derqui N, Tolosa-Wright M, Jonnerby J, Wang L, Baldwin S, Pillay TD, Thwaites RS, Luca C, Varro R, Badhan A, Parker E, Rosadas C, McClure M, Tedder R, Taylor G, Lalvani A; INSTINCT Study Investigators. Fenn J, et al. Among authors: koycheva a. EBioMedicine. 2024 Dec 11;111:105475. doi: 10.1016/j.ebiom.2024.105475. Online ahead of print. EBioMedicine. 2024. PMID: 39667271 Free article.
Rapid emergence of transmissible SARS-CoV-2 variants in mild community cases.
Crone MA, Hakki S, Fenn J, Zhou J, Oliveira CRd, Madon KJ, Koycheva A, Badhan A, Jonnerby J, Nevin S, Conibear E, Derelle R, Varro R, Luca C, Ahmad S, Zambon M, Barclay WS, Dunning J, Freemont PS, Taylor GP, Lalvani A. Crone MA, et al. Among authors: koycheva a. Microbiol Spectr. 2024 Apr 2;12(4):e0363423. doi: 10.1128/spectrum.03634-23. Epub 2024 Mar 14. Microbiol Spectr. 2024. PMID: 38483161 Free PMC article. No abstract available.
A pro-inflammatory gut mucosal cytokine response is associated with mild COVID-19 disease and superior induction of serum antibodies.
Costigan D, Fenn J, Yen S, Ilott N, Bullers S, Hale J, Greenhalf W, Conibear E, Koycheva A, Madon K, Jahan I, Huang M, Badhan A, Parker E, Rosadas C, Jones K, McClure M, Tedder R, Taylor G, Baillie KJ, Semple MG, Openshaw PJM, Pearson C, Johnson J; INSTINCT Study Group; ISARIC4C investigators; Lalvani A, Thornton EE. Costigan D, et al. Among authors: koycheva a. Mucosal Immunol. 2024 Feb;17(1):111-123. doi: 10.1016/j.mucimm.2023.11.005. Epub 2023 Nov 22. Mucosal Immunol. 2024. PMID: 37995912 Free PMC article.
Risk factors and vectors for SARS-CoV-2 household transmission: a prospective, longitudinal cohort study.
Derqui N, Koycheva A, Zhou J, Pillay TD, Crone MA, Hakki S, Fenn J, Kundu R, Varro R, Conibear E, Madon KJ, Barnett JL, Houston H, Singanayagam A, Narean JS, Tolosa-Wright MR, Mosscrop L, Rosadas C, Watber P, Anderson C, Parker E, Freemont PS, Ferguson NM, Zambon M, McClure MO, Tedder R, Barclay WS, Dunning J, Taylor GP, Lalvani A; INSTINCT and ATACCC study group. Derqui N, et al. Among authors: koycheva a. Lancet Microbe. 2023 Jun;4(6):e397-e408. doi: 10.1016/S2666-5247(23)00069-1. Epub 2023 Apr 6. Lancet Microbe. 2023. PMID: 37031689 Free PMC article.
Onset and window of SARS-CoV-2 infectiousness and temporal correlation with symptom onset: a prospective, longitudinal, community cohort study.
Hakki S, Zhou J, Jonnerby J, Singanayagam A, Barnett JL, Madon KJ, Koycheva A, Kelly C, Houston H, Nevin S, Fenn J, Kundu R, Crone MA, Pillay TD, Ahmad S, Derqui-Fernandez N, Conibear E, Freemont PS, Taylor GP, Ferguson N, Zambon M, Barclay WS, Dunning J, Lalvani A; ATACCC study investigators. Hakki S, et al. Among authors: koycheva a. Lancet Respir Med. 2022 Nov;10(11):1061-1073. doi: 10.1016/S2213-2600(22)00226-0. Epub 2022 Aug 18. Lancet Respir Med. 2022. PMID: 35988572 Free PMC article.
Cross-reactive memory T cells associate with protection against SARS-CoV-2 infection in COVID-19 contacts.
Kundu R, Narean JS, Wang L, Fenn J, Pillay T, Fernandez ND, Conibear E, Koycheva A, Davies M, Tolosa-Wright M, Hakki S, Varro R, McDermott E, Hammett S, Cutajar J, Thwaites RS, Parker E, Rosadas C, McClure M, Tedder R, Taylor GP, Dunning J, Lalvani A. Kundu R, et al. Among authors: koycheva a. Nat Commun. 2022 Jan 10;13(1):80. doi: 10.1038/s41467-021-27674-x. Nat Commun. 2022. PMID: 35013199 Free PMC article.
Broadening symptom criteria improves early case identification in SARS-CoV-2 contacts.
Houston H, Hakki S, Pillay TD, Madon K, Derqui-Fernandez N, Koycheva A, Singanayagam A, Fenn J, Kundu R, Conibear E, Varro R, Cutajar J, Quinn V, Wang L, Narean JS, Tolosa-Wright MR, Barnett J, Kon OM, Tedder R, Taylor G, Zambon M, Ferguson N, Dunning J, Deeks JJ, Lalvani A. Houston H, et al. Among authors: koycheva a. Eur Respir J. 2022 Jul 7;60(1):2102308. doi: 10.1183/13993003.02308-2021. Print 2022 Jul. Eur Respir J. 2022. PMID: 34824057 Free PMC article.
Community transmission and viral load kinetics of the SARS-CoV-2 delta (B.1.617.2) variant in vaccinated and unvaccinated individuals in the UK: a prospective, longitudinal, cohort study.
Singanayagam A, Hakki S, Dunning J, Madon KJ, Crone MA, Koycheva A, Derqui-Fernandez N, Barnett JL, Whitfield MG, Varro R, Charlett A, Kundu R, Fenn J, Cutajar J, Quinn V, Conibear E, Barclay W, Freemont PS, Taylor GP, Ahmad S, Zambon M, Ferguson NM, Lalvani A; ATACCC Study Investigators. Singanayagam A, et al. Among authors: koycheva a. Lancet Infect Dis. 2022 Feb;22(2):183-195. doi: 10.1016/S1473-3099(21)00648-4. Epub 2021 Oct 29. Lancet Infect Dis. 2022. PMID: 34756186 Free PMC article.