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Page 1
Oral administration of obeldesivir protects nonhuman primates against Sudan ebolavirus.
Cross RW, Woolsey C, Chu VC, Babusis D, Bannister R, Vermillion MS, Geleziunas R, Barrett KT, Bunyan E, Nguyen AQ, Cihlar T, Porter DP, Prasad AN, Deer DJ, Borisevich V, Agans KN, Martinez J, Harrison MB, Dobias NS, Fenton KA, Bilello JP, Geisbert TW. Cross RW, et al. Among authors: bunyan e. Science. 2024 Mar 15;383(6688):eadk6176. doi: 10.1126/science.adk6176. Epub 2024 Mar 15. Science. 2024. PMID: 38484056
Combination therapy with remdesivir and monoclonal antibodies protects nonhuman primates against advanced Sudan virus disease.
Cross RW, Bornholdt ZA, Prasad AN, Woolsey C, Borisevich V, Agans KN, Deer DJ, Abelson DM, Kim DH, Shestowsky WS, Campbell LA, Bunyan E, Geisbert JB, Dobias NS, Fenton KA, Porter DP, Zeitlin L, Geisbert TW. Cross RW, et al. Among authors: bunyan e. JCI Insight. 2022 May 23;7(10):e159090. doi: 10.1172/jci.insight.159090. JCI Insight. 2022. PMID: 35413016 Free PMC article.
Combination therapy protects macaques against advanced Marburg virus disease.
Cross RW, Bornholdt ZA, Prasad AN, Borisevich V, Agans KN, Deer DJ, Abelson DM, Kim DH, Shestowsky WS, Campbell LA, Bunyan E, Geisbert JB, Fenton KA, Zeitlin L, Porter DP, Geisbert TW. Cross RW, et al. Among authors: bunyan e. Nat Commun. 2021 Mar 25;12(1):1891. doi: 10.1038/s41467-021-22132-0. Nat Commun. 2021. PMID: 33767178 Free PMC article.
Discovery of GS-5245 (Obeldesivir), an Oral Prodrug of Nucleoside GS-441524 That Exhibits Antiviral Efficacy in SARS-CoV-2-Infected African Green Monkeys.
Mackman RL, Kalla RV, Babusis D, Pitts J, Barrett KT, Chun K, Du Pont V, Rodriguez L, Moshiri J, Xu Y, Lee M, Lee G, Bleier B, Nguyen AQ, O'Keefe BM, Ambrosi A, Cook M, Yu J, Dempah KE, Bunyan E, Riola NC, Lu X, Liu R, Davie A, Hsiang TY, Dearing J, Vermillion M, Gale M Jr, Niedziela-Majka A, Feng JY, Hedskog C, Bilello JP, Subramanian R, Cihlar T. Mackman RL, et al. Among authors: bunyan e. J Med Chem. 2023 Sep 14;66(17):11701-11717. doi: 10.1021/acs.jmedchem.3c00750. Epub 2023 Aug 19. J Med Chem. 2023. PMID: 37596939 Free PMC article.
Remdesivir efficacy against yellow fever in a hamster model.
Julander JG, Bunyan E, Jordan R, Porter DP. Julander JG, et al. Among authors: bunyan e. Antiviral Res. 2022 Jul;203:105331. doi: 10.1016/j.antiviral.2022.105331. Epub 2022 May 6. Antiviral Res. 2022. PMID: 35533777
Prevention and therapy of SARS-CoV-2 and the B.1.351 variant in mice.
Martinez DR, Schaefer A, Leist SR, Li D, Gully K, Yount B, Feng JY, Bunyan E, Porter DP, Cihlar T, Montgomery SA, Haynes BF, Baric RS, Nussenzweig MC, Sheahan TP. Martinez DR, et al. Among authors: bunyan e. bioRxiv [Preprint]. 2021 Apr 14:2021.01.27.428478. doi: 10.1101/2021.01.27.428478. bioRxiv. 2021. Update in: Cell Rep. 2021 Jul 27;36(4):109450. doi: 10.1016/j.celrep.2021.109450 PMID: 33532765 Free PMC article. Updated. Preprint.
Prevention and therapy of SARS-CoV-2 and the B.1.351 variant in mice.
Martinez DR, Schäfer A, Leist SR, Li D, Gully K, Yount B, Feng JY, Bunyan E, Porter DP, Cihlar T, Montgomery SA, Haynes BF, Baric RS, Nussenzweig MC, Sheahan TP. Martinez DR, et al. Among authors: bunyan e. Cell Rep. 2021 Jul 27;36(4):109450. doi: 10.1016/j.celrep.2021.109450. Epub 2021 Jul 10. Cell Rep. 2021. PMID: 34289384 Free PMC article.
Tissue-Resident Alveolar Macrophages Reduce Ozone-induced Inflammation via MerTK-mediated Efferocytosis.
Guttenberg MA, Vose AT, Birukova A, Lewars K, Cumming RI, Albright MC, Mark JI, Salazar CJ, Swaminathan S, Yu Z, Sokolenko YV, Bunyan E, Yaeger MJ, Fessler MB, Que LG, Gowdy KM, Misharin AV, Tighe RM. Guttenberg MA, et al. Among authors: bunyan e. Am J Respir Cell Mol Biol. 2024 Jun;70(6):493-506. doi: 10.1165/rcmb.2023-0390OC. Am J Respir Cell Mol Biol. 2024. PMID: 38386777
14 results