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Page 1
Oral administration of obeldesivir protects nonhuman primates against Sudan ebolavirus.
Cross RW, Woolsey C, Chu VC, Babusis D, Bannister R, Vermillion MS, Geleziunas R, Barrett KT, Bunyan E, Nguyen AQ, Cihlar T, Porter DP, Prasad AN, Deer DJ, Borisevich V, Agans KN, Martinez J, Harrison MB, Dobias NS, Fenton KA, Bilello JP, Geisbert TW. Cross RW, et al. Among authors: geleziunas r. Science. 2024 Mar 15;383(6688):eadk6176. doi: 10.1126/science.adk6176. Epub 2024 Mar 15. Science. 2024. PMID: 38484056
Arenavirus-Based Vectors Generate Robust SIV Immunity in Non-Human Primates.
Sharma B, Bekerman E, Truong H, Lee J, Gamez-Guerrero M, Boopathy A, Mital R, Huang KB, Ahmadi-Erber S, Wimmer R, Schulha S, Lauterbach H, Orlinger K, Suthram S, Lewis MG, Blair W, Makadzange T, Geleziunas R, Murry JP, Schmidt S. Sharma B, et al. Among authors: geleziunas r. Vaccines (Basel). 2024 Jul 2;12(7):735. doi: 10.3390/vaccines12070735. Vaccines (Basel). 2024. PMID: 39066373 Free PMC article.
HIV-1 envelope diversity and sensitivity to broadly neutralizing antibodies across stages of acute HIV-1 infection.
VanderVeen LA, Selzer L, Moldt B, Parvangada A, Li J, Ananworanich J, Crowell TA, Eron JJ, Daar ES, Haubrich R, Geleziunas R, Cyktor J, Mellors JW, Callebaut C. VanderVeen LA, et al. Among authors: geleziunas r. AIDS. 2024 Mar 15;38(4):607-610. doi: 10.1097/QAD.0000000000003792. Epub 2023 Nov 16. AIDS. 2024. PMID: 38416554 Free PMC article.
Immunogenic arenavirus vector SIV vaccine reduces setpoint viral load in SIV-challenged rhesus monkeys.
Boopathy AV, Sharma B, Nekkalapudi A, Wimmer R, Gamez-Guerrero M, Suthram S, Truong H, Lee J, Li J, Martin R, Blair W, Geleziunas R, Orlinger K, Ahmadi-Erber S, Lauterbach H, Makadzange T, Falkard B, Schmidt S. Boopathy AV, et al. Among authors: geleziunas r. NPJ Vaccines. 2023 Nov 10;8(1):175. doi: 10.1038/s41541-023-00768-x. NPJ Vaccines. 2023. PMID: 37945621 Free PMC article.
Antiretroviral therapy reveals triphasic decay of intact SIV genomes and persistence of ancestral variants.
Fray EJ, Wu F, Simonetti FR, Zitzmann C, Sambaturu N, Molina-Paris C, Bender AM, Liu PT, Ventura JD, Wiseman RW, O'Connor DH, Geleziunas R, Leitner T, Ribeiro RM, Perelson AS, Barouch DH, Siliciano JD, Siliciano RF. Fray EJ, et al. Among authors: geleziunas r. Cell Host Microbe. 2023 Mar 8;31(3):356-372.e5. doi: 10.1016/j.chom.2023.01.016. Epub 2023 Feb 20. Cell Host Microbe. 2023. PMID: 36809762 Free PMC article.
Safety, immunogenicity and effect on viral rebound of HTI vaccines in early treated HIV-1 infection: a randomized, placebo-controlled phase 1 trial.
Bailón L, Llano A, Cedeño S, Escribà T, Rosás-Umbert M, Parera M, Casadellà M, Lopez M, Pérez F, Oriol-Tordera B, Ruiz-Riol M, Coll J, Perez F, Rivero À, Leselbaum AR, McGowan I, Sengupta D, Wee EG, Hanke T, Paredes R, Alarcón-Soto Y, Clotet B, Noguera-Julian M, Brander C, Molto J, Mothe B; AELIX002 Study Group. Bailón L, et al. Nat Med. 2022 Dec;28(12):2611-2621. doi: 10.1038/s41591-022-02060-2. Epub 2022 Oct 27. Nat Med. 2022. PMID: 36302893 Clinical Trial.
Flt3 agonist enhances immunogenicity of arenavirus vector-based simian immunodeficiency virus vaccine in macaques.
Boopathy AV, Nekkalapudi A, Sung J, Schulha S, Jin D, Sharma B, Ng S, Lu S, Wimmer R, Suthram S, Ahmadi-Erber S, Lauterbach H, Orlinger KK, Hung M, Carr B, Callebaut C, Geleziunas R, Kuhne M, Schmidt S, Falkard B. Boopathy AV, et al. Among authors: geleziunas r. J Virol. 2024 Jul 23;98(7):e0029424. doi: 10.1128/jvi.00294-24. Epub 2024 Jun 3. J Virol. 2024. PMID: 38829139 Free PMC article.
Therapeutic efficacy of combined active and passive immunization in ART-suppressed, SHIV-infected rhesus macaques.
Walker-Sperling VEK, Mercado NB, Chandrashekar A, Borducchi EN, Liu J, Nkolola JP, Lewis M, Murry JP, Yang Y, Geleziunas R, Robb ML, Michael NL, Pau MG, Wegmann F, Schuitemaker H, Fray EJ, Kumar MR, Siliciano JD, Siliciano RF, Barouch DH. Walker-Sperling VEK, et al. Among authors: geleziunas r. Nat Commun. 2022 Jun 16;13(1):3463. doi: 10.1038/s41467-022-31196-5. Nat Commun. 2022. PMID: 35710819 Free PMC article.
Therapeutic efficacy of an Ad26/MVA vaccine with SIV gp140 protein and vesatolimod in ART-suppressed rhesus macaques.
Ventura JD, Nkolola JP, Chandrashekar A, Borducchi EN, Liu J, Mercado NB, Hope DL, Giffin VM, McMahan K, Geleziunas R, Murry JP, Yang Y, Lewis MG, Pau MG, Wegmann F, Schuitemaker H, Fray EJ, Kumar MR, Siliciano JD, Siliciano RF, Robb ML, Michael NL, Barouch DH. Ventura JD, et al. Among authors: geleziunas r. NPJ Vaccines. 2022 May 18;7(1):53. doi: 10.1038/s41541-022-00477-x. NPJ Vaccines. 2022. PMID: 35585080 Free PMC article.
108 results