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A redox switch allows binding of Fe(II) and Fe(III) ions in the cyanobacterial iron-binding protein FutA from Prochlorococcus.
Bolton R, Machelett MM, Stubbs J, Axford D, Caramello N, Catapano L, Malý M, Rodrigues MJ, Cordery C, Tizzard GJ, MacMillan F, Engilberge S, von Stetten D, Tosha T, Sugimoto H, Worrall JAR, Webb JS, Zubkov M, Coles S, Mathieu E, Steiner RA, Murshudov G, Schrader TE, Orville AM, Royant A, Evans G, Hough MA, Owen RL, Tews I. Bolton R, et al. Among authors: hough ma. Proc Natl Acad Sci U S A. 2024 Mar 19;121(12):e2308478121. doi: 10.1073/pnas.2308478121. Epub 2024 Mar 15. Proc Natl Acad Sci U S A. 2024. PMID: 38489389 Free PMC article.
Serial Femtosecond Crystallography Reveals the Role of Water in the One- or Two-Electron Redox Chemistry of Compound I in the Catalytic Cycle of the B-Type Dye-Decolorizing Peroxidase DtpB.
Lučić M, Wilson MT, Tosha T, Sugimoto H, Shilova A, Axford D, Owen RL, Hough MA, Worrall JAR. Lučić M, et al. Among authors: hough ma. ACS Catal. 2022 Nov 4;12(21):13349-13359. doi: 10.1021/acscatal.2c03754. Epub 2022 Oct 18. ACS Catal. 2022. PMID: 36366763 Free PMC article.
Dose-resolved serial synchrotron and XFEL structures of radiation-sensitive metalloproteins.
Ebrahim A, Moreno-Chicano T, Appleby MV, Chaplin AK, Beale JH, Sherrell DA, Duyvesteyn HME, Owada S, Tono K, Sugimoto H, Strange RW, Worrall JAR, Axford D, Owen RL, Hough MA. Ebrahim A, et al. Among authors: hough ma. IUCrJ. 2019 May 3;6(Pt 4):543-551. doi: 10.1107/S2052252519003956. eCollection 2019 Jul 1. IUCrJ. 2019. PMID: 31316799 Free PMC article.
High-throughput structures of protein-ligand complexes at room temperature using serial femtosecond crystallography.
Moreno-Chicano T, Ebrahim A, Axford D, Appleby MV, Beale JH, Chaplin AK, Duyvesteyn HME, Ghiladi RA, Owada S, Sherrell DA, Strange RW, Sugimoto H, Tono K, Worrall JAR, Owen RL, Hough MA. Moreno-Chicano T, et al. Among authors: hough ma. IUCrJ. 2019 Oct 10;6(Pt 6):1074-1085. doi: 10.1107/S2052252519011655. eCollection 2019 Nov 1. IUCrJ. 2019. PMID: 31709063 Free PMC article.
Serial Femtosecond Zero Dose Crystallography Captures a Water-Free Distal Heme Site in a Dye-Decolorising Peroxidase to Reveal a Catalytic Role for an Arginine in FeIV =O Formation.
Lučić M, Svistunenko DA, Wilson MT, Chaplin AK, Davy B, Ebrahim A, Axford D, Tosha T, Sugimoto H, Owada S, Dworkowski FSN, Tews I, Owen RL, Hough MA, Worrall JAR. Lučić M, et al. Among authors: hough ma. Angew Chem Int Ed Engl. 2020 Nov 23;59(48):21656-21662. doi: 10.1002/anie.202008622. Epub 2020 Sep 23. Angew Chem Int Ed Engl. 2020. PMID: 32780931 Free PMC article.
93 results