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PD-1 regulates ILC3-driven intestinal immunity and homeostasis.
Jacquelot N, Xiong L, Cao WHJ, Huang Q, Yu H, Sayad A, Anttila CJA, Baldwin TM, Hickey PF, Amann-Zalcenstein D, Ohashi PS, Nutt SL, Belz GT, Seillet C. Jacquelot N, et al. Among authors: ohashi ps. Mucosal Immunol. 2024 Jun;17(3):371-386. doi: 10.1016/j.mucimm.2024.03.002. Epub 2024 Mar 16. Mucosal Immunol. 2024. PMID: 38492744 Free article.
Identification of antigenic epitopes recognized by tumor infiltrating lymphocytes in high grade serous ovarian cancer by multi-omics profiling of the auto-antigen repertoire.
Millar DG, Yang SYC, Sayad A, Zhao Q, Nguyen LT, Warner K, Sangster AG, Nakatsugawa M, Murata K, Wang BX, Shaw P, Clarke B, Bernardini MQ, Pugh T, Thibault P, Hirano N, Perreault C, Ohashi PS. Millar DG, et al. Among authors: ohashi ps. Cancer Immunol Immunother. 2023 Jul;72(7):2375-2392. doi: 10.1007/s00262-023-03413-7. Epub 2023 Mar 21. Cancer Immunol Immunother. 2023. PMID: 36943460 Free PMC article.
Combined Transcriptome and Circulating Tumor DNA Longitudinal Biomarker Analysis Associates With Clinical Outcomes in Advanced Solid Tumors Treated With Pembrolizumab.
Hernando-Calvo A, Yang SYC, Vila-Casadesús M, Han M, Liu ZA, Berman AHK, Spreafico A, Razak AA, Lheureux S, Hansen AR, Lo Giacco D, Abbas-Aghababazadeh F, Matito J, Haibe-Kains B, Pugh TJ, Bratman SV, Aleshin A, Berche R, Saavedra O, Garralda E, Elston S, Siu LL, Ohashi PS, Vivancos A, Bedard PL. Hernando-Calvo A, et al. Among authors: ohashi ps. JCO Precis Oncol. 2024 Aug;8:e2400100. doi: 10.1200/PO.24.00100. JCO Precis Oncol. 2024. PMID: 39178369 Free PMC article. Clinical Trial.
Characterization of innate lymphoid cell subsets infiltrating melanoma and epithelial ovarian tumors.
Chung DC, Ghaedi M, Warner K, Sayad A, Saibil SD, Bernardini MQ, Clarke BA, Shaw PA, Butler MO, Easson A, Morrissy S, Wang BX, Nguyen L, Ohashi PS, Jacquelot N. Chung DC, et al. Among authors: ohashi ps. Oncoimmunology. 2024 May 10;13(1):2349347. doi: 10.1080/2162402X.2024.2349347. eCollection 2024. Oncoimmunology. 2024. PMID: 38746870 Free PMC article.
Generation of an Inhibitory NK Cell Subset by TGF-β1/IL-15 Polarization.
Chung DC, Garcia-Batres CR, Millar DG, Wong SWY, Elford AR, Mathews JA, Wang BX, Nguyen LT, Shaw PA, Clarke BA, Bernardini MQ, Sacher AG, Crome SQ, Ohashi PS. Chung DC, et al. Among authors: ohashi ps. J Immunol. 2024 Jun 15;212(12):1904-1912. doi: 10.4049/jimmunol.2300834. J Immunol. 2024. PMID: 38668728 Free PMC article.
B Cells Promote T Cell Immunosenescence and Mammalian Aging Parameters.
Khan S, Chakraborty M, Wu F, Chen N, Wang T, Chan YT, Sayad A, Vásquez JDS, Kotlyar M, Nguyen K, Huang Y, Alibhai FJ, Woo M, Li RK, Husain M, Jurisica I, Gehring AJ, Ohashi PS, Furman D, Tsai S, Winer S, Winer DA. Khan S, et al. Among authors: ohashi ps. bioRxiv [Preprint]. 2023 Sep 14:2023.09.12.556363. doi: 10.1101/2023.09.12.556363. bioRxiv. 2023. PMID: 38529494 Free PMC article. Preprint.
Ex vivo activation of the GCN2 pathway metabolically reprograms T cells, leading to enhanced adoptive cell therapy.
St Paul M, Saibil SD, Kates M, Han S, Lien SC, Laister RC, Hezaveh K, Kloetgen A, Penny S, Guo T, Garcia-Batres C, Smith LK, Chung DC, Elford AR, Sayad A, Pinto D, Mak TW, Hirano N, McGaha T, Ohashi PS. St Paul M, et al. Among authors: ohashi ps. Cell Rep Med. 2024 Mar 19;5(3):101465. doi: 10.1016/j.xcrm.2024.101465. Epub 2024 Mar 8. Cell Rep Med. 2024. PMID: 38460518 Free PMC article.
Early Changes in Tumor-Naive Cell-Free Methylomes and Fragmentomes Predict Outcomes in Pembrolizumab-Treated Solid Tumors.
Stutheit-Zhao EY, Sanz-Garcia E, Liu ZA, Wong D, Marsh K, Abdul Razak AR, Spreafico A, Bedard PL, Hansen AR, Lheureux S, Torti D, Lam B, Yang SYC, Burgener J, Luo P, Zeng Y, Cheng N, Awadalla P, Bratman SV, Ohashi PS, Pugh TJ, Siu LL. Stutheit-Zhao EY, et al. Among authors: ohashi ps. Cancer Discov. 2024 Jun 3;14(6):1048-1063. doi: 10.1158/2159-8290.CD-23-1060. Cancer Discov. 2024. PMID: 38393391 Free PMC article.
315 results