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Large-scale genome-wide association study of 398,238 women unveils seven novel loci associated with high-grade serous epithelial ovarian cancer risk.
Barnes DR, Tyrer JP, Dennis J, Leslie G, Bolla MK, Lush M, Aeilts AM, Aittomäki K, Andrieu N, Andrulis IL, Anton-Culver H, Arason A, Arun BK, Balmaña J, Bandera EV, Barkardottir RB, Berger LPV, de Gonzalez AB, Berthet P, Białkowska K, Bjørge L, Blanco AM, Blok MJ, Bobolis KA, Bogdanova NV, Brenton JD, Butz H, Buys SS, Caligo MA, Campbell I, Castillo C, Claes KBM; GEMO Study Collaborators; EMBRACE Collaborators; Colonna SV, Cook LS, Daly MB, Dansonka-Mieszkowska A, de la Hoya M, deFazio A, DePersia A, Ding YC, Domchek SM, Dörk T, Einbeigi Z, Engel C, Evans DG, Foretova L, Fortner RT, Fostira F, Foti MC, Friedman E, Frone MN, Ganz PA, Gentry-Maharaj A, Glendon G, Godwin AK, González-Neira A, Greene MH, Gronwald J, Guerrieri-Gonzaga A, Hamann U, Hansen TVO, Harris HR, Hauke J, Heitz F, Hogervorst FBL, Hooning MJ, Hopper JL, Huff CD, Huntsman DG, Imyanitov EN; kConFab Investigators; Izatt L, Jakubowska A, James PA, Janavicius R, John EM, Kar S, Karlan BY, Kennedy CJ, Kiemeney LALM, Konstantopoulou I, Kupryjanczyk J, Laitman Y, Lavie O, Lawrenson K, Lester J, Lesueur F, Lopez-Pleguezuelos C, Mai PL, Manoukian S, May T, McNeish IA, Menon U, Milne RL, Modugno F, Mongiovi JM, Monta… See abstract for full author list ➔ Barnes DR, et al. Among authors: huntsman dg. medRxiv [Preprint]. 2024 Mar 4:2024.02.29.24303243. doi: 10.1101/2024.02.29.24303243. medRxiv. 2024. PMID: 38496424 Free PMC article. Preprint.
Refined cut-off for TP53 immunohistochemistry improves prediction of TP53 mutation status in ovarian mucinous tumors: implications for outcome analyses.
Kang EY, Cheasley D, LePage C, Wakefield MJ, da Cunha Torres M, Rowley S, Salazar C, Xing Z, Allan P, Bowtell DDL, Mes-Masson AM, Provencher DM, Rahimi K, Kelemen LE, Fasching PA, Doherty JA, Goodman MT, Goode EL, Deen S, Pharoah PDP, Brenton JD, Sieh W, Mateoiu C, Sundfeldt K, Cook LS, Le ND, Anglesio MS, Gilks CB, Huntsman DG, Kennedy CJ, Traficante N; Australian Ovarian Cancer Study; DeFazio A, Kaufmann S, Churchman M, Gourley C, Stephens AN, Meagher NS, Ramus SJ, Antill YC, Campbell I, Scott CL, Köbel M, Gorringe KL; GAMuT Collaborators. Kang EY, et al. Among authors: huntsman dg. Mod Pathol. 2021 Jan;34(1):194-206. doi: 10.1038/s41379-020-0618-9. Epub 2020 Jul 28. Mod Pathol. 2021. PMID: 32724153 Free PMC article.
Validation and clinical performance of a single test, DNA based endometrial cancer molecular classifier.
Jamieson A, Grube M, Kommoss F, Lum A, Leung S, Chiu D, Henderson G, Heitz F, Heublein S, Zeimet AG, Hasenburg A, Diebold J, Walter C, Staebler A, Reynolds J, Lapuk A, McConechy MK, Huntsman DG, Gilks B, Kommoss S, McAlpine JN. Jamieson A, et al. Among authors: huntsman dg. Int J Gynecol Cancer. 2024 Dec 2;34(12):1888-1897. doi: 10.1136/ijgc-2024-005916. Int J Gynecol Cancer. 2024. PMID: 39461743
The unique metabolome of clear cell ovarian carcinoma.
Ji JX, Hoang LN, Cochrane DR, Lum A, Senz J, Farnell D, Tessier-Cloutier B, Huntsman DG, Klein Geltink RI. Ji JX, et al. Among authors: huntsman dg. J Pathol. 2024 Oct;264(2):160-173. doi: 10.1002/path.6329. Epub 2024 Aug 3. J Pathol. 2024. PMID: 39096103
Changes in the tumour microenvironment mark the transition from serous borderline tumour to low-grade serous carcinoma.
Vallejos R, Zhantuyakova A, Negri GL, Martin SD, Spencer SE, Thornton S, Leung S, Lynch B, Qin Y, Chow C, Liang B, Zdravko S, Douglas JM, Milne K, Mateyko B, Nelson BH, Howitt BE, Kommoss FK, Horn LC, Hoang L, Singh N, Morin GB, Huntsman DG, Cochrane D. Vallejos R, et al. Among authors: huntsman dg. J Pathol. 2024 Oct;264(2):197-211. doi: 10.1002/path.6338. Epub 2024 Jul 31. J Pathol. 2024. PMID: 39081243
Learning generalizable AI models for multi-center histopathology image classification.
Asadi-Aghbolaghi M, Darbandsari A, Zhang A, Contreras-Sanz A, Boschman J, Ahmadvand P, Köbel M, Farnell D, Huntsman DG, Churg A, Black PC, Wang G, Gilks CB, Farahani H, Bashashati A. Asadi-Aghbolaghi M, et al. Among authors: huntsman dg. NPJ Precis Oncol. 2024 Jul 19;8(1):151. doi: 10.1038/s41698-024-00652-4. NPJ Precis Oncol. 2024. PMID: 39030380 Free PMC article.
AI-based histopathology image analysis reveals a distinct subset of endometrial cancers.
Darbandsari A, Farahani H, Asadi M, Wiens M, Cochrane D, Khajegili Mirabadi A, Jamieson A, Farnell D, Ahmadvand P, Douglas M, Leung S, Abolmaesumi P, Jones SJM, Talhouk A, Kommoss S, Gilks CB, Huntsman DG, Singh N, McAlpine JN, Bashashati A. Darbandsari A, et al. Among authors: huntsman dg. Nat Commun. 2024 Jun 26;15(1):4973. doi: 10.1038/s41467-024-49017-2. Nat Commun. 2024. PMID: 38926357 Free PMC article.
339 results