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Die Wechselwirkung mit ribosomalen Proteinen begleitet die Stressinduktion des Wirkstoffkandidaten BOLD-100/KP1339 im endoplasmatischen Retikulum.
Neuditschko B, Legin AA, Baier D, Schintlmeister A, Reipert S, Wagner M, Keppler BK, Berger W, Meier-Menches SM, Gerner C. Neuditschko B, et al. Among authors: berger w. Angew Chem Weinheim Bergstr Ger. 2021 Mar 1;133(10):5121-5126. doi: 10.1002/ange.202015962. Epub 2021 Feb 1. Angew Chem Weinheim Bergstr Ger. 2021. PMID: 38505777 Free PMC article.
Intrinsic and acquired forms of resistance against the anticancer ruthenium compound KP1019 [indazolium trans-[tetrachlorobis(1H-indazole)ruthenate (III)] (FFC14A).
Heffeter P, Pongratz M, Steiner E, Chiba P, Jakupec MA, Elbling L, Marian B, Körner W, Sevelda F, Micksche M, Keppler BK, Berger W. Heffeter P, et al. Among authors: berger w. J Pharmacol Exp Ther. 2005 Jan;312(1):281-9. doi: 10.1124/jpet.104.073395. Epub 2004 Aug 26. J Pharmacol Exp Ther. 2005. PMID: 15331656
Anticancer activity of the lanthanum compound [tris(1,10-phenanthroline)lanthanum(III)]trithiocyanate (KP772; FFC24).
Heffeter P, Jakupec MA, Körner W, Wild S, von Keyserlingk NG, Elbling L, Zorbas H, Korynevska A, Knasmüller S, Sutterlüty H, Micksche M, Keppler BK, Berger W. Heffeter P, et al. Among authors: berger w. Biochem Pharmacol. 2006 Feb 14;71(4):426-40. doi: 10.1016/j.bcp.2005.11.009. Epub 2005 Dec 15. Biochem Pharmacol. 2006. PMID: 16343446
{(1R,2R,4R)-4-methyl-1,2-cyclohexanediamine}oxalatoplatinum(II): a novel enantiomerically pure oxaliplatin derivative showing improved anticancer activity in vivo.
Abramkin SA, Jungwirth U, Valiahdi SM, Dworak C, Habala L, Meelich K, Berger W, Jakupec MA, Hartinger CG, Nazarov AA, Galanski MS, Keppler BK. Abramkin SA, et al. Among authors: berger w. J Med Chem. 2010 Oct 28;53(20):7356-64. doi: 10.1021/jm100953c. J Med Chem. 2010. PMID: 20886814 Free PMC article.
1,168 results