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Structural basis for Mis18 complex assembly and its implications for centromere maintenance.
Thamkachy R, Medina-Pritchard B, Park SH, Chiodi CG, Zou J, de la Torre-Barranco M, Shimanaka K, Abad MA, Gallego Páramo C, Feederle R, Ruksenaite E, Heun P, Davies OR, Rappsilber J, Schneidman-Duhovny D, Cho US, Jeyaprakash AA. Thamkachy R, et al. Among authors: heun p. EMBO Rep. 2024 Aug;25(8):3348-3372. doi: 10.1038/s44319-024-00183-w. Epub 2024 Jul 1. EMBO Rep. 2024. PMID: 38951710 Free PMC article.
Efficient formation of single-copy human artificial chromosomes.
Gambogi CW, Birchak GJ, Mer E, Brown DM, Yankson G, Kixmoeller K, Gavade JN, Espinoza JL, Kashyap P, Dupont CL, Logsdon GA, Heun P, Glass JI, Black BE. Gambogi CW, et al. Among authors: heun p. Science. 2024 Mar 22;383(6689):1344-1349. doi: 10.1126/science.adj3566. Epub 2024 Mar 21. Science. 2024. PMID: 38513017 Free PMC article.
Spt6 is a maintenance factor for centromeric CENP-A.
Bobkov GOM, Huang A, van den Berg SJW, Mitra S, Anselm E, Lazou V, Schunter S, Feederle R, Imhof A, Lusser A, Jansen LET, Heun P. Bobkov GOM, et al. Among authors: heun p. Nat Commun. 2020 Jun 10;11(1):2919. doi: 10.1038/s41467-020-16695-7. Nat Commun. 2020. PMID: 32522980 Free PMC article.
Drosophila SWR1 and NuA4 complexes are defined by DOMINO isoforms.
Scacchetti A, Schauer T, Reim A, Apostolou Z, Campos Sparr A, Krause S, Heun P, Wierer M, Becker PB. Scacchetti A, et al. Among authors: heun p. Elife. 2020 May 20;9:e56325. doi: 10.7554/eLife.56325. Elife. 2020. PMID: 32432549 Free PMC article.
Reconstituting Drosophila Centromere Identity in Human Cells.
Roure V, Medina-Pritchard B, Lazou V, Rago L, Anselm E, Venegas D, Jeyaprakash AA, Heun P. Roure V, et al. Among authors: heun p. Cell Rep. 2019 Oct 8;29(2):464-479.e5. doi: 10.1016/j.celrep.2019.08.067. Cell Rep. 2019. PMID: 31597104 Free PMC article.
Human Artificial Chromosomes that Bypass Centromeric DNA.
Logsdon GA, Gambogi CW, Liskovykh MA, Barrey EJ, Larionov V, Miga KH, Heun P, Black BE. Logsdon GA, et al. Among authors: heun p. Cell. 2019 Jul 25;178(3):624-639.e19. doi: 10.1016/j.cell.2019.06.006. Cell. 2019. PMID: 31348889 Free PMC article.
37 results