Van Loy T - Search Results

1

High-affinity ELR+ chemokine ligands show G protein bias over β-arrestin recruitment and receptor internalization in CXCR1 signaling.

Boon K, Vanalken N, Szpakowska M, Chevigné A, Schols D, Van Loy T. Boon K, et al. Among authors: van loy t. J Biol Chem. 2024 Nov 29;301(1):108044. doi: 10.1016/j.jbc.2024.108044. Online ahead of print. J Biol Chem. 2024. PMID: 39615686 Free article.

2

Insight into structural properties of viral G protein-coupled receptors and their role in the viral infection: IUPHAR Review 41.

Tsutsumi N, Kildedal DF, Hansen OK, Kong Q, Schols D, Van Loy T, Rosenkilde MM. Tsutsumi N, et al. Among authors: van loy t. Br J Pharmacol. 2025 Jan;182(1):26-51. doi: 10.1111/bph.17379. Epub 2024 Oct 23. Br J Pharmacol. 2025. PMID: 39443818 Review.

3

Rigid Macrocycle Metal Complexes as CXCR4 Chemokine Receptor Antagonists: Influence of Ring Size.

Renard I, D'huys T, Burke BP, Ajoleza T, Cain AN, Funwie NL, Khan A, Maples DL, Maples RD, Matz DL, McRobbie G, Ullom R, Prior TJ, Linder DP, Van Loy T, Hubin TJ, Schols D, Archibald SJ. Renard I, et al. Among authors: van loy t. Pharmaceutics. 2024 Jul 28;16(8):1000. doi: 10.3390/pharmaceutics16081000. Pharmaceutics. 2024. PMID: 39204345 Free PMC article.

4

Systematic Assessment of Human CCR7 Signalling Using NanoBRET Biosensors Points towards the Importance of the Cellular Context.

Vanalken N, Boon K, Szpakowska M, Chevigné A, Schols D, Van Loy T. Vanalken N, et al. Among authors: van loy t. Biosensors (Basel). 2024 Mar 14;14(3):142. doi: 10.3390/bios14030142. Biosensors (Basel). 2024. PMID: 38534251 Free PMC article.

5

Second generation Al¹⁸F-labeled D-amino acid peptide for CXCR4 targeted molecular imaging.

Spahn MA, Luyten K, Van Loy T, Sathekge M, Deroose CM, Koole M, Schols D, Vanduffel W, De Vos K, Annaert P, Bormans G, Cleeren F. Spahn MA, et al. Among authors: van loy t. Nucl Med Biol. 2024 May-Jun;132-133:108906. doi: 10.1016/j.nucmedbio.2024.108906. Epub 2024 Mar 19. Nucl Med Biol. 2024. PMID: 38518400

6

trans-IV restriction: a new configuration for metal bis-cyclam complexes as potent CXCR4 inhibitors.

Alzahrani SO, McRobbie G, Khan A, D'huys T, Van Loy T, Walker AN, Renard I, Hubin TJ, Schols D, Burke BP, Archibald SJ. Alzahrani SO, et al. Among authors: van loy t. Dalton Trans. 2024 Mar 19;53(12):5616-5623. doi: 10.1039/d3dt01729j. Dalton Trans. 2024. PMID: 38439632 Free PMC article.

7

Systematic assessment of chemokine ligand bias at the human chemokine receptor CXCR2 indicates G protein bias over β-arrestin recruitment and receptor internalization.

Boon K, Vanalken N, Szpakowska M, Chevigné A, Schols D, Van Loy T. Boon K, et al. Among authors: van loy t. Cell Commun Signal. 2024 Jan 17;22(1):43. doi: 10.1186/s12964-023-01460-2. Cell Commun Signal. 2024. PMID: 38233929 Free PMC article.

8

Development of a cellular model to study CCR8 signaling in tumor-infiltrating regulatory T cells.

Liu L, Rangan L, Vanalken N, Kong Q, Schlenner S, De Jonghe S, Schols D, Van Loy T. Liu L, et al. Among authors: van loy t. Cancer Immunol Immunother. 2024 Jan 17;73(1):11. doi: 10.1007/s00262-023-03607-z. Cancer Immunol Immunother. 2024. PMID: 38231448 Free PMC article.

9

REGA-SIGN: Development of a Novel Set of NanoBRET-Based G Protein Biosensors.

Boon K, Vanalken N, Meyen E, Schols D, Van Loy T. Boon K, et al. Among authors: van loy t. Biosensors (Basel). 2023 Jul 28;13(8):767. doi: 10.3390/bios13080767. Biosensors (Basel). 2023. PMID: 37622853 Free PMC article.

10

Synthesis and structure-activity relationship study of phenoxybenzylpiperazine analogues as CCR8 agonists.

Li Q, Claes S, Verhaegen Y, Anthonissen S, Van Loy T, Schols D, Dehaen W, De Jonghe S. Li Q, et al. Among authors: van loy t. Bioorg Chem. 2023 Oct;139:106755. doi: 10.1016/j.bioorg.2023.106755. Epub 2023 Jul 28. Bioorg Chem. 2023. PMID: 37544272

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