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A High Threshold of Biotherapeutic Aggregate Numbers is Needed to Induce an Immunogenic Response In Vitro, In Vivo, and in the Clinic.
Cohen JR, Brych SR, Prabhu S, Bi V, Elbaradei A, Tokuda JM, Xiang C, Hokom M, Cui X, Ly C, Amos N, Sun J, Calamba D, Herskovitz J, Capili A, Nourbakhsh K, Merlo A, Carreon J, Wypych J, Narhi LO, Jawa V, Joubert MK. Cohen JR, et al. Among authors: capili a. Pharm Res. 2024 Apr;41(4):651-672. doi: 10.1007/s11095-024-03678-2. Epub 2024 Mar 22. Pharm Res. 2024. PMID: 38519817
Experimental validation of a parenteral permitted daily exposure value for cleaning-induced degradants from recombinant therapeutic proteins with in vitro immunogenicity assays.
Cohen JR, Joubert MK, Tabassum S, Capili A, Carreon J, Xiang C, Prabhu S, Merlo A, Mytych D, Dolan DG, Kouda R. Cohen JR, et al. Among authors: capili a. J Pharm Sci. 2024 Oct 28:S0022-3549(24)00490-8. doi: 10.1016/j.xphs.2024.10.041. Online ahead of print. J Pharm Sci. 2024. PMID: 39490658
LincRNA-Cox2 Regulates Smoke-induced Inflammation in Murine Macrophages.
Salih MM, Robinson EK, Malekos E, Perez E, Capili A, Kim K, Zhang WZ, Cloonan SM, Carpenter S. Salih MM, et al. Among authors: capili a. Am J Respir Cell Mol Biol. 2023 May;68(5):511-522. doi: 10.1165/rcmb.2022-0413OC. Am J Respir Cell Mol Biol. 2023. PMID: 36657060
Cytokine response over the course of COVID-19 infection in pregnant women.
Rosen DB, Murphy EA, Gejman RS, Capili A, Friedlander RL, Rand S, Cagino KA, Glynn SM, Matthews KC, Kubiak JM, Yee J, Prabhu M, Riley LE, Yang YJ. Rosen DB, et al. Among authors: capili a. Cytokine. 2022 Jun;154:155894. doi: 10.1016/j.cyto.2022.155894. Epub 2022 Apr 25. Cytokine. 2022. PMID: 35490452 Free PMC article.
Angiopoietin 2 Is Associated with Vascular Necroptosis Induction in Coronavirus Disease 2019 Acute Respiratory Distress Syndrome.
Price DR, Benedetti E, Hoffman KL, Gomez-Escobar L, Alvarez-Mulett S, Capili A, Sarwath H, Parkhurst CN, Lafond E, Weidman K, Ravishankar A, Cheong JG, Batra R, Büyüközkan M, Chetnik K, Easthausen I, Schenck EJ, Racanelli AC, Outtz Reed H, Laurence J, Josefowicz SZ, Lief L, Choi ME, Schmidt F, Borczuk AC, Choi AMK, Krumsiek J, Rafii S. Price DR, et al. Among authors: capili a. Am J Pathol. 2022 Jul;192(7):1001-1015. doi: 10.1016/j.ajpath.2022.04.002. Epub 2022 Apr 22. Am J Pathol. 2022. PMID: 35469796 Free PMC article.
Reversal of emphysema by restoration of pulmonary endothelial cells.
Hisata S, Racanelli AC, Kermani P, Schreiner R, Houghton S, Palikuqi B, Kunar B, Zhou A, McConn K, Capili A, Redmond D, Nolan DJ, Ginsberg M, Ding BS, Martinez FJ, Scandura JM, Cloonan SM, Rafii S, Choi AMK. Hisata S, et al. Among authors: capili a. J Exp Med. 2021 Aug 2;218(8):e20200938. doi: 10.1084/jem.20200938. Epub 2021 Jul 21. J Exp Med. 2021. PMID: 34287647 Free PMC article.
Macrophage Exosomes Resolve Atherosclerosis by Regulating Hematopoiesis and Inflammation via MicroRNA Cargo.
Bouchareychas L, Duong P, Covarrubias S, Alsop E, Phu TA, Chung A, Gomes M, Wong D, Meechoovet B, Capili A, Yamamoto R, Nakauchi H, McManus MT, Carpenter S, Van Keuren-Jensen K, Raffai RL. Bouchareychas L, et al. Among authors: capili a. Cell Rep. 2020 Jul 14;32(2):107881. doi: 10.1016/j.celrep.2020.107881. Cell Rep. 2020. PMID: 32668250 Free PMC article.
26 results