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21 results

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Page 1
First-in-human trial evaluating safety and pharmacokinetics of AT-752, a novel nucleotide prodrug with pan-serotype activity against dengue virus.
Zhou X-J, Lickliter J, Montrond M, Ishak L, Pietropaolo K, James D, Belanger B, Horga A, Hammond J. Zhou X-J, et al. Among authors: ishak l. Antimicrob Agents Chemother. 2024 May 2;68(5):e0161523. doi: 10.1128/aac.01615-23. Epub 2024 Mar 25. Antimicrob Agents Chemother. 2024. PMID: 38526047 Free PMC article. Clinical Trial.
Oral bemnifosbuvir (AT-527) vs placebo in patients with mild-to-moderate COVID-19 in an outpatient setting (MORNINGSKY).
Horga A, Saenz R, Yilmaz G, Simón-Campos A, Pietropaolo K, Stubbings WJ, Collinson N, Ishak L, Zrinscak B, Belanger B, Granier C, Lin K, C Hurt A, Zhou XJ, Wildum S, Hammond J. Horga A, et al. Among authors: ishak l. Future Virol. 2023 Oct:10.2217/fvl-2023-0115. doi: 10.2217/fvl-2023-0115. Epub 2023 Nov 1. Future Virol. 2023. PMID: 37928891 Free PMC article.
Disease causing mutation (P178L) in mitochondrial transcription factor A results in impaired mitochondrial transcription initiation.
Mehmedović M, Martucci M, Spåhr H, Ishak L, Mishra A, Sanchez-Sandoval ME, Pardo-Hernández C, Peter B, van den Wildenberg SM, Falkenberg M, Farge G. Mehmedović M, et al. Among authors: ishak l. Biochim Biophys Acta Mol Basis Dis. 2022 Oct 1;1868(10):166467. doi: 10.1016/j.bbadis.2022.166467. Epub 2022 Jun 15. Biochim Biophys Acta Mol Basis Dis. 2022. PMID: 35716868 Free article.
A first-in-human study of BLZ-100 (tozuleristide) demonstrates tolerability and safety in skin cancer patients.
Yamada M, Miller DM, Lowe M, Rowe C, Wood D, Soyer HP, Byrnes-Blake K, Parrish-Novak J, Ishak L, Olson JM, Brandt G, Griffin P, Spelman L, Prow TW. Yamada M, et al. Among authors: ishak l. Contemp Clin Trials Commun. 2021 Aug 4;23:100830. doi: 10.1016/j.conctc.2021.100830. eCollection 2021 Sep. Contemp Clin Trials Commun. 2021. PMID: 34401600 Free PMC article.
Phase 1 Safety, Pharmacokinetics, and Fluorescence Imaging Study of Tozuleristide (BLZ-100) in Adults With Newly Diagnosed or Recurrent Gliomas.
Patil CG, Walker DG, Miller DM, Butte P, Morrison B, Kittle DS, Hansen SJ, Nufer KL, Byrnes-Blake KA, Yamada M, Lin LL, Pham K, Perry J, Parrish-Novak J, Ishak L, Prow T, Black K, Mamelak AN. Patil CG, et al. Among authors: ishak l. Neurosurgery. 2019 Oct 1;85(4):E641-E649. doi: 10.1093/neuros/nyz125. Neurosurgery. 2019. PMID: 31069381 Clinical Trial.
Real-time Visualization of Breast Carcinoma in Pathology Specimens From Patients Receiving Fluorescent Tumor-Marking Agent Tozuleristide.
Dintzis SM, Hansen S, Harrington KM, Tan LC, Miller DM, Ishak L, Parrish-Novak J, Kittle D, Perry J, Gombotz C, Fortney T, Porenta S, Hales L, Calhoun KE, Anderson BO, Javid SH, Byrd DR. Dintzis SM, et al. Among authors: ishak l. Arch Pathol Lab Med. 2019 Sep;143(9):1076-1083. doi: 10.5858/arpa.2018-0197-OA. Epub 2018 Dec 14. Arch Pathol Lab Med. 2019. PMID: 30550350 Free article. Clinical Trial.
Selective mitochondrial DNA degradation following double-strand breaks.
Moretton A, Morel F, Macao B, Lachaume P, Ishak L, Lefebvre M, Garreau-Balandier I, Vernet P, Falkenberg M, Farge G. Moretton A, et al. Among authors: ishak l. PLoS One. 2017 Apr 28;12(4):e0176795. doi: 10.1371/journal.pone.0176795. eCollection 2017. PLoS One. 2017. PMID: 28453550 Free PMC article.
Autophagy controls the pathogenicity of OPA1 mutations in dominant optic atrophy.
Kane MS, Alban J, Desquiret-Dumas V, Gueguen N, Ishak L, Ferre M, Amati-Bonneau P, Procaccio V, Bonneau D, Lenaers G, Reynier P, Chevrollier A. Kane MS, et al. Among authors: ishak l. J Cell Mol Med. 2017 Oct;21(10):2284-2297. doi: 10.1111/jcmm.13149. Epub 2017 Apr 4. J Cell Mol Med. 2017. PMID: 28378518 Free PMC article.
21 results