Thomas L - Search Results

1

Inhibitory protein-protein interactions of the SIRT1 deacetylase are choreographed by post-translational modification.

Krzysiak TC, Choi YJ, Kim YJ, Yang Y, DeHaven C, Thompson L, Ponticelli R, Mermigos MM, Thomas L, Marquez A, Sipula I, Kemper JK, Jurczak M, Thomas G, Gronenborn AM. Krzysiak TC, et al. Among authors: thomas g, thomas l. Protein Sci. 2024 Apr;33(4):e4938. doi: 10.1002/pro.4938. Protein Sci. 2024. PMID: 38533551

2

An Insulin-Responsive Sensor in the SIRT1 Disordered Region Binds DBC1 and PACS-2 to Control Enzyme Activity.

Krzysiak TC, Thomas L, Choi YJ, Auclair S, Qian Y, Luan S, Krasnow SM, Thomas LL, Koharudin LMI, Benos PV, Marks DL, Gronenborn AM, Thomas G. Krzysiak TC, et al. Among authors: thomas ll, thomas g, thomas l. Mol Cell. 2018 Dec 20;72(6):985-998.e7. doi: 10.1016/j.molcel.2018.10.007. Epub 2018 Nov 8. Mol Cell. 2018. PMID: 30415949 Free PMC article.

3

Neural deficits in a mouse model of PACS1 syndrome are corrected with PACS1- or HDAC6-targeting therapy.

Villar-Pazos S, Thomas L, Yang Y, Chen K, Lyles JB, Deitch BJ, Ochaba J, Ling K, Powers B, Gingras S, Kordasiewicz HB, Grubisha MJ, Huang YH, Thomas G. Villar-Pazos S, et al. Among authors: thomas g, thomas l. Nat Commun. 2023 Oct 17;14(1):6547. doi: 10.1038/s41467-023-42176-8. Nat Commun. 2023. PMID: 37848409 Free PMC article.

4

Caught in the act - protein adaptation and the expanding roles of the PACS proteins in tissue homeostasis and disease.

Thomas G, Aslan JE, Thomas L, Shinde P, Shinde U, Simmen T. Thomas G, et al. Among authors: thomas l. J Cell Sci. 2017 Jun 1;130(11):1865-1876. doi: 10.1242/jcs.199463. Epub 2017 May 5. J Cell Sci. 2017. PMID: 28476937 Free PMC article. Review.

5

The multifunctional sorting protein PACS-2 regulates SIRT1-mediated deacetylation of p53 to modulate p21-dependent cell-cycle arrest.

Atkins KM, Thomas LL, Barroso-González J, Thomas L, Auclair S, Yin J, Kang H, Chung JH, Dikeakos JD, Thomas G. Atkins KM, et al. Among authors: thomas ll, thomas g, thomas l. Cell Rep. 2014 Sep 11;8(5):1545-57. doi: 10.1016/j.celrep.2014.07.049. Epub 2014 Aug 21. Cell Rep. 2014. PMID: 25159152 Free PMC article.

6

RNA-targeted therapy corrects neuronal deficits in PACS1 syndrome mice.

Villar-Pazos S, Thomas L, Yang Y, Chen K, Lyles JB, Deitch BJ, Ochaba J, Ling K, Powers B, Gingras S, Kordasiewicz HB, Grubisha MJ, Huang YH, Thomas G. Villar-Pazos S, et al. Among authors: thomas g, thomas l. Res Sq [Preprint]. 2023 Jan 27:rs.3.rs-2440581. doi: 10.21203/rs.3.rs-2440581/v1. Res Sq. 2023. Update in: Nat Commun. 2023 Oct 17;14(1):6547. doi: 10.1038/s41467-023-42176-8 PMID: 36747781 Free PMC article. Updated. Preprint.

7

Rab32 uses its effector reticulon 3L to trigger autophagic degradation of mitochondria-associated membrane (MAM) proteins.

Herrera-Cruz MS, Yap MC, Tahbaz N, Phillips K, Thomas L, Thomas G, Simmen T. Herrera-Cruz MS, et al. Among authors: thomas g, thomas l. Biol Direct. 2021 Nov 7;16(1):22. doi: 10.1186/s13062-021-00311-9. Biol Direct. 2021. PMID: 34743744 Free PMC article.

8

A PACS-1, GGA3 and CK2 complex regulates CI-MPR trafficking.

Scott GK, Fei H, Thomas L, Medigeshi GR, Thomas G. Scott GK, et al. Among authors: thomas g, thomas l. EMBO J. 2006 Oct 4;25(19):4423-35. doi: 10.1038/sj.emboj.7601336. Epub 2006 Sep 14. EMBO J. 2006. PMID: 16977309 Free PMC article.

9

PACS-2 mediates the ATM and NF-κB-dependent induction of anti-apoptotic Bcl-xL in response to DNA damage.

Barroso-González J, Auclair S, Luan S, Thomas L, Atkins KM, Aslan JE, Thomas LL, Zhao J, Zhao Y, Thomas G. Barroso-González J, et al. Among authors: thomas ll, thomas g, thomas l. Cell Death Differ. 2016 Sep 1;23(9):1448-57. doi: 10.1038/cdd.2016.23. Epub 2016 Mar 4. Cell Death Differ. 2016. PMID: 26943323 Free PMC article.

10

Cell-type specific processing of neuroendocrine precursor proteins using vaccinia recombinants.

Thomas G, Thomas L, Thorne BA, Herbert E. Thomas G, et al. Among authors: thomas l. Biochimie. 1988 Jan;70(1):89-97. doi: 10.1016/0300-9084(88)90163-0. Biochimie. 1988. PMID: 3135846

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