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Page 1
Functional analysis of cell lines derived from SMAD3-related Loeys-Dietz syndrome patients provides insights into genotype-phenotype relation.
de Wagenaar NP, van den Bersselaar LM, Odijk HJHM, Stefens SJM, Reinhardt DP, Roos-Hesselink JW, Kanaar R, Verhagen JMA, Brüggenwirth HT, van de Laar IMBH, van der Pluijm I, Essers J. de Wagenaar NP, et al. Among authors: van der pluijm i. Hum Mol Genet. 2024 Jun 5;33(12):1090-1104. doi: 10.1093/hmg/ddae044. Hum Mol Genet. 2024. PMID: 38538566 Free PMC article.
Extracellular matrix defects in aneurysmal Fibulin-4 mice predispose to lung emphysema.
Ramnath NW, van de Luijtgaarden KM, van der Pluijm I, van Nimwegen M, van Heijningen PM, Swagemakers SM, van Thiel BS, Ridwan RY, van Vliet N, Vermeij M, Hawinkels LJ, de Munck A, Dzyubachyk O, Meijering E, van der Spek P, Rottier R, Yanagisawa H, Hendriks RW, Kanaar R, Rouwet EV, Kleinjan A, Essers J. Ramnath NW, et al. Among authors: van thiel bs, van de luijtgaarden km, van der pluijm i, van heijningen pm, van nimwegen m, van vliet n, van der spek p. PLoS One. 2014 Sep 25;9(9):e106054. doi: 10.1371/journal.pone.0106054. eCollection 2014. PLoS One. 2014. PMID: 25255451 Free PMC article.
The renin-angiotensin system and its involvement in vascular disease.
van Thiel BS, van der Pluijm I, te Riet L, Essers J, Danser AH. van Thiel BS, et al. Among authors: van der pluijm i. Eur J Pharmacol. 2015 Sep 15;763(Pt A):3-14. doi: 10.1016/j.ejphar.2015.03.090. Epub 2015 May 16. Eur J Pharmacol. 2015. PMID: 25987425 Review.
AT1-receptor blockade, but not renin inhibition, reduces aneurysm growth and cardiac failure in fibulin-4 mice.
Te Riet L, van Deel ED, van Thiel BS, Moltzer E, van Vliet N, Ridwan Y, van Veghel R, van Heijningen PM, Robertus JL, Garrelds IM, Vermeij M, van der Pluijm I, Danser AH, Essers J. Te Riet L, et al. Among authors: van veghel r, van thiel bs, van heijningen pm, van der pluijm i, van vliet n, van deel ed. J Hypertens. 2016 Apr;34(4):654-65. doi: 10.1097/HJH.0000000000000845. J Hypertens. 2016. PMID: 26828783
Defective Connective Tissue Remodeling in Smad3 Mice Leads to Accelerated Aneurysmal Growth Through Disturbed Downstream TGF-β Signaling.
van der Pluijm I, van Vliet N, von der Thusen JH, Robertus JL, Ridwan Y, van Heijningen PM, van Thiel BS, Vermeij M, Hoeks SE, Buijs-Offerman RMGB, Verhagen HJM, Kanaar R, Bertoli-Avella AM, Essers J. van der Pluijm I, et al. Among authors: van thiel bs, van heijningen pm, van vliet n. EBioMedicine. 2016 Oct;12:280-294. doi: 10.1016/j.ebiom.2016.09.006. Epub 2016 Sep 10. EBioMedicine. 2016. PMID: 27688095 Free PMC article.
Decreased mitochondrial respiration in aneurysmal aortas of Fibulin-4 mutant mice is linked to PGC1A regulation.
van der Pluijm I, Burger J, van Heijningen PM, IJpma A, van Vliet N, Milanese C, Schoonderwoerd K, Sluiter W, Ringuette LJ, Dekkers DHW, Que I, Kaijzel EL, Te Riet L, MacFarlane EG, Das D, van der Linden R, Vermeij M, Demmers JA, Mastroberardino PG, Davis EC, Yanagisawa H, Dietz HC, Kanaar R, Essers J. van der Pluijm I, et al. Among authors: van heijningen pm, van der linden r, van vliet n. Cardiovasc Res. 2018 Nov 1;114(13):1776-1793. doi: 10.1093/cvr/cvy150. Cardiovasc Res. 2018. PMID: 29931197 Free PMC article.
Gestational jet lag predisposes to later-life skeletal and cardiac disease.
Chaves I, van der Eerden B, Boers R, Boers J, Streng AA, Ridwan Y, Schreuders-Koedam M, Vermeulen M, van der Pluijm I, Essers J, Gribnau J, Reiss IKM, van der Horst GTJ. Chaves I, et al. Among authors: van der eerden b, van der pluijm i, van der horst gtj. Chronobiol Int. 2019 May;36(5):657-671. doi: 10.1080/07420528.2019.1579734. Epub 2019 Feb 22. Chronobiol Int. 2019. PMID: 30793958
Fibulin-4 deficiency differentially affects cytoskeleton structure and dynamics as well as TGFβ signaling.
Burger J, van Vliet N, van Heijningen P, Kumra H, Kremers GJ, Alves M, van Cappellen G, Yanagisawa H, Reinhardt DP, Kanaar R, van der Pluijm I, Essers J. Burger J, et al. Among authors: van cappellen g, van der pluijm i, van vliet n, van heijningen p. Cell Signal. 2019 Jun;58:65-78. doi: 10.1016/j.cellsig.2019.02.008. Epub 2019 Mar 4. Cell Signal. 2019. PMID: 30844428 Free article.
Inflammation and TGF-β Signaling Differ between Abdominal Aneurysms and Occlusive Disease.
IJpma A, Te Riet L, van de Luijtgaarden KM, van Heijningen PM, Burger J, Majoor-Krakauer D, Rouwet EV, Essers J, Verhagen HJM, van der Pluijm I. IJpma A, et al. Among authors: van de luijtgaarden km, van heijningen pm, van der pluijm i. J Cardiovasc Dev Dis. 2019 Nov 1;6(4):38. doi: 10.3390/jcdd6040038. J Cardiovasc Dev Dis. 2019. PMID: 31683995 Free PMC article.
Slc2a10 knock-out mice deficient in ascorbic acid synthesis recapitulate aspects of arterial tortuosity syndrome and display mitochondrial respiration defects.
Boel A, Burger J, Vanhomwegen M, Beyens A, Renard M, Barnhoorn S, Casteleyn C, Reinhardt DP, Descamps B, Vanhove C, van der Pluijm I, Coucke P, Willaert A, Essers J, Callewaert B. Boel A, et al. Among authors: van der pluijm i. Hum Mol Genet. 2020 Jun 3;29(9):1476-1488. doi: 10.1093/hmg/ddaa071. Hum Mol Genet. 2020. PMID: 32307537
57 results