Striessnig J - Search Results

1

Pathogenicity of de novo CACNA1D Ca²⁺ channel variants predicted from sequence co-variation.

Tang X, Ortner NJ, Nikonishyna YV, Fernández-Quintero ML, Kokot J, Striessnig J, Liedl KR. Tang X, et al. Among authors: striessnig j. Eur J Hum Genet. 2024 Sep;32(9):1065-1073. doi: 10.1038/s41431-024-01594-y. Epub 2024 Mar 29. Eur J Hum Genet. 2024. PMID: 38553610 Free PMC article.

2

C-terminal modulatory domain controls coupling of voltage-sensing to pore opening in Cav1.3 L-type Ca(2+) channels.

Lieb A, Ortner N, Striessnig J. Lieb A, et al. Among authors: striessnig j. Biophys J. 2014 Apr 1;106(7):1467-75. doi: 10.1016/j.bpj.2014.02.017. Biophys J. 2014. PMID: 24703308 Free PMC article.

3

Pyrimidine-2,4,6-triones are a new class of voltage-gated L-type Ca2+ channel activators.

Ortner NJ, Bock G, Vandael DH, Mauersberger R, Draheim HJ, Gust R, Carbone E, Tuluc P, Striessnig J. Ortner NJ, et al. Among authors: striessnig j. Nat Commun. 2014 Jun 19;5:3897. doi: 10.1038/ncomms4897. Nat Commun. 2014. PMID: 24941892 Free PMC article.

4

CACNA1D de novo mutations in autism spectrum disorders activate Cav1.3 L-type calcium channels.

Pinggera A, Lieb A, Benedetti B, Lampert M, Monteleone S, Liedl KR, Tuluc P, Striessnig J. Pinggera A, et al. Among authors: striessnig j. Biol Psychiatry. 2015 May 1;77(9):816-22. doi: 10.1016/j.biopsych.2014.11.020. Epub 2014 Dec 8. Biol Psychiatry. 2015. PMID: 25620733 Free PMC article.

5

Pharmacology of L-type Calcium Channels: Novel Drugs for Old Targets?

Striessnig J, Ortner NJ, Pinggera A. Striessnig J, et al. Curr Mol Pharmacol. 2015;8(2):110-22. doi: 10.2174/1874467208666150507105845. Curr Mol Pharmacol. 2015. PMID: 25966690 Free PMC article. Review.

6

L-type calcium channels as drug targets in CNS disorders.

Ortner NJ, Striessnig J. Ortner NJ, et al. Among authors: striessnig j. Channels (Austin). 2016;10(1):7-13. doi: 10.1080/19336950.2015.1048936. Epub 2015 Jun 3. Channels (Austin). 2016. PMID: 26039257 Free PMC article. Review.

7

A Polybasic Plasma Membrane Binding Motif in the I-II Linker Stabilizes Voltage-gated CaV1.2 Calcium Channel Function.

Kaur G, Pinggera A, Ortner NJ, Lieb A, Sinnegger-Brauns MJ, Yarov-Yarovoy V, Obermair GJ, Flucher BE, Striessnig J. Kaur G, et al. Among authors: striessnig j. J Biol Chem. 2015 Aug 21;290(34):21086-21100. doi: 10.1074/jbc.M115.645671. Epub 2015 Jun 22. J Biol Chem. 2015. PMID: 26100638 Free PMC article.

8

Ca_v 1.3 (CACNA1D) L-type Ca²⁺ channel dysfunction in CNS disorders.

Pinggera A, Striessnig J. Pinggera A, et al. Among authors: striessnig j. J Physiol. 2016 Oct 15;594(20):5839-5849. doi: 10.1113/JP270672. Epub 2016 Feb 29. J Physiol. 2016. PMID: 26842699 Free PMC article. Review.

9

New gain-of-function mutation shows CACNA1D as recurrently mutated gene in autism spectrum disorders and epilepsy.

Pinggera A, Mackenroth L, Rump A, Schallner J, Beleggia F, Wollnik B, Striessnig J. Pinggera A, et al. Among authors: striessnig j. Hum Mol Genet. 2017 Aug 1;26(15):2923-2932. doi: 10.1093/hmg/ddx175. Hum Mol Genet. 2017. PMID: 28472301 Free PMC article.

10

Lower Affinity of Isradipine for L-Type Ca²⁺ Channels during Substantia Nigra Dopamine Neuron-Like Activity: Implications for Neuroprotection in Parkinson's Disease.

Ortner NJ, Bock G, Dougalis A, Kharitonova M, Duda J, Hess S, Tuluc P, Pomberger T, Stefanova N, Pitterl F, Ciossek T, Oberacher H, Draheim HJ, Kloppenburg P, Liss B, Striessnig J. Ortner NJ, et al. Among authors: striessnig j. J Neurosci. 2017 Jul 12;37(28):6761-6777. doi: 10.1523/JNEUROSCI.2946-16.2017. Epub 2017 Jun 7. J Neurosci. 2017. PMID: 28592699 Free PMC article.

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