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Preclinical assessment of the PI3Kα selective inhibitor inavolisib and prediction of its pharmacokinetics and efficacious dose in human.
Salphati L, Pang J, Plise EG, Cheong J, Braun MG, Friedman LS, Hong Thibodeau R, Jaochico A, Johnson R, Liu N, Nannini M, Sampath D, Song K, Hannan EJ, Staben ST. Salphati L, et al. Among authors: sampath d. Xenobiotica. 2024 Oct;54(10):808-820. doi: 10.1080/00498254.2024.2415103. Epub 2024 Dec 4. Xenobiotica. 2024. PMID: 39387185
LP-118 is a novel B-cell lymphoma 2 / extra-large inhibitor that demonstrates efficacy in models of venetoclaxresistant chronic lymphocytic leukemia.
Ravikrishnan J, Diaz-Rohena DY, Muhowski E, Mo X, Lai TH, Misra S, Williams CD, Sanchez J, Mitchell A, Satpati S, Perry E, Kaufman T, Liu C, Lozanski A, Lozanski G, Rogers K, Kittai AS, Bhat SA, Collins MC, Davids MS, Jain N, Wierda WG, Lapalombella R, Byrd JC, Tan F, Chen Y, Chen Y, Shen Y, Anthony SP, Woyach JA, Sampath D. Ravikrishnan J, et al. Among authors: sampath d. Haematologica. 2025 Jan 1;110(1):78-91. doi: 10.3324/haematol.2023.284353. Haematologica. 2025. PMID: 39113656 Free PMC article.
Neonatal exposure to a neuroactive steroid alters low-frequency oscillations in the subiculum.
Fine-Raquet B, Manzella FM, Joksimovic SM, Dietz RM, Orfila JE, Sampath D, Tesic V, Atluri N, Covey DF, Raol YH, Jevtovic-Todorovic V, Herson PS, Todorovic SM. Fine-Raquet B, et al. Among authors: sampath d. Exp Biol Med (Maywood). 2023 Apr;248(7):578-587. doi: 10.1177/15353702231177009. Epub 2023 Jun 13. Exp Biol Med (Maywood). 2023. PMID: 37309730 Free PMC article.
218 results