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Identification of clickable HIV-1 capsid-targeting probes for viral replication inhibition.
McFadden WM, Casey-Moore MC, Bare GAL, Kirby KA, Wen X, Li G, Wang H, Slack RL, Snyder AA, Lorson ZC, Kaufman IL, Cilento ME, Tedbury PR, Gembicky M, Olson AJ, Torbett BE, Sharpless KB, Sarafianos SG. McFadden WM, et al. Among authors: torbett be. Cell Chem Biol. 2024 Mar 21;31(3):477-486.e7. doi: 10.1016/j.chembiol.2024.02.012. Cell Chem Biol. 2024. PMID: 38518746
A lentiviral vector B cell gene therapy platform for the delivery of the anti-HIV-1 eCD4-Ig-knob-in-hole-reversed immunoadhesin.
Vamva E, Ozog S, Leaman DP, Yu-Hong Cheng R, Irons NJ, Ott A, Stoffers C, Khan I, Goebrecht GKE, Gardner MR, Farzan M, Rawlings DJ, Zwick MB, James RG, Torbett BE. Vamva E, et al. Among authors: torbett be. Mol Ther Methods Clin Dev. 2023 Feb 11;28:366-384. doi: 10.1016/j.omtm.2023.02.004. eCollection 2023 Mar 9. Mol Ther Methods Clin Dev. 2023. PMID: 36879849 Free PMC article.
Activation of HIV-1 proviruses increases downstream chromatin accessibility.
Shah R, Gallardo CM, Jung YH, Clock B, Dixon JR, McFadden WM, Majumder K, Pintel DJ, Corces VG, Torbett BE, Tedbury PR, Sarafianos SG. Shah R, et al. Among authors: torbett be. iScience. 2022 Nov 8;25(12):105490. doi: 10.1016/j.isci.2022.105490. eCollection 2022 Dec 22. iScience. 2022. PMID: 36505924 Free PMC article.
Hexokinase 3 enhances myeloid cell survival via non-glycolytic functions.
Seiler K, Humbert M, Minder P, Mashimo I, Schläfli AM, Krauer D, Federzoni EA, Vu B, Moresco JJ, Yates JR 3rd, Sadowski MC, Radpour R, Kaufmann T, Sarry JE, Dengjel J, Tschan MP, Torbett BE. Seiler K, et al. Among authors: torbett be. Cell Death Dis. 2022 May 11;13(5):448. doi: 10.1038/s41419-022-04891-w. Cell Death Dis. 2022. PMID: 35538058 Free PMC article.
Assessment of safety and immunogenicity of MHC homozygous iPSC-derived CD34+ hematopoietic progenitors in an NHP model.
D'Souza SS, Kumar A, Maufort J, Weinfurter JT, Raymond M, Strelchenko NS, Perrin E, Coonen J, Mejia A, Simmons HA, Torbett BE, Reynolds M, Thomson JA, Slukvin II. D'Souza SS, et al. Among authors: torbett be. Blood Adv. 2022 Sep 27;6(18):5267-5278. doi: 10.1182/bloodadvances.2022006984. Blood Adv. 2022. PMID: 35404997 Free PMC article.
138 results