Shi G - Search Results

1

Inhibition of HIV-1 release by ADAM metalloproteinase inhibitors.

Ireland J, Segura J, Shi G, Buchwald J, Roth G, Shen TJ, Wang R, Ji X, Fischer ER, Moir S, Chun TW, Sun PD. Ireland J, et al. Among authors: shi g. Front Microbiol. 2024 Mar 20;15:1385775. doi: 10.3389/fmicb.2024.1385775. eCollection 2024. Front Microbiol. 2024. PMID: 38572241 Free PMC article.

2

Dynamic roles of arginine residues 82 and 92 of Escherichia coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: crystallographic studies.

Blaszczyk J, Li Y, Shi G, Yan H, Ji X. Blaszczyk J, et al. Among authors: shi g. Biochemistry. 2003 Feb 18;42(6):1573-80. doi: 10.1021/bi0267994. Biochemistry. 2003. PMID: 12578370

3

Essential roles of a dynamic loop in the catalysis of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.

Blaszczyk J, Li Y, Wu Y, Shi G, Ji X, Yan H. Blaszczyk J, et al. Among authors: shi g. Biochemistry. 2004 Feb 17;43(6):1469-77. doi: 10.1021/bi036053l. Biochemistry. 2004. PMID: 14769023

4

Reaction trajectory of pyrophosphoryl transfer catalyzed by 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.

Blaszczyk J, Shi G, Li Y, Yan H, Ji X. Blaszczyk J, et al. Among authors: shi g. Structure. 2004 Mar;12(3):467-75. doi: 10.1016/j.str.2004.02.003. Structure. 2004. PMID: 15016362 Free article.

5

New ways to derivatize at position 6 of 7,7-dimethyl-7,8-dihydropterin.

Shi G, Ji X. Shi G, et al. Tetrahedron Lett. 2011 Nov 16;52(46):6174-6176. doi: 10.1016/j.tetlet.2011.09.047. Tetrahedron Lett. 2011. PMID: 22125346 Free PMC article.

6

Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: New design with improved properties.

Shi G, Shaw G, Liang YH, Subburaman P, Li Y, Wu Y, Yan H, Ji X. Shi G, et al. Bioorg Med Chem. 2012 Jan 1;20(1):47-57. doi: 10.1016/j.bmc.2011.11.032. Epub 2011 Nov 23. Bioorg Med Chem. 2012. PMID: 22169600 Free PMC article.

7

Bisubstrate analog inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: new lead exhibits a distinct binding mode.

Shi G, Shaw G, Li Y, Wu Y, Yan H, Ji X. Shi G, et al. Bioorg Med Chem. 2012 Jul 15;20(14):4303-9. doi: 10.1016/j.bmc.2012.05.060. Epub 2012 Jun 6. Bioorg Med Chem. 2012. PMID: 22727779 Free PMC article.

8

Structural enzymology and inhibition of the bi-functional folate pathway enzyme HPPK-DHPS from the biowarfare agent Francisella tularensis.

Shaw GX, Li Y, Shi G, Wu Y, Cherry S, Needle D, Zhang D, Tropea JE, Waugh DS, Yan H, Ji X. Shaw GX, et al. Among authors: shi g. FEBS J. 2014 Sep;281(18):4123-37. doi: 10.1111/febs.12896. Epub 2014 Jul 23. FEBS J. 2014. PMID: 24975935 Free PMC article.

9

Design, synthesis, and anticancer activity evaluation of irreversible allosteric inhibitors of the ubiquitin-conjugating enzyme Ube2g2.

Wang C, Shi G, Ji X. Wang C, et al. Among authors: shi g. Medchemcomm. 2018 Aug 20;9(11):1818-1825. doi: 10.1039/c8md00320c. eCollection 2018 Nov 1. Medchemcomm. 2018. PMID: 30542531 Free PMC article.

10

Bisubstrate inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: Transition state analogs for high affinity binding.

Shi G, Shaw GX, Zhu F, Tarasov SG, Ji X. Shi G, et al. Bioorg Med Chem. 2021 Jan 1;29:115847. doi: 10.1016/j.bmc.2020.115847. Epub 2020 Nov 9. Bioorg Med Chem. 2021. PMID: 33199204 Free PMC article.

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