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Page 1
Pulmonary SARS-CoV-2 infection leads to para-infectious immune activation in the brain.
Dunai C, Hetherington C, Boardman SA, Clark JJ, Sharma P, Subramaniam K, Tharmaratnam K, Needham EJ, Williams R, Huang Y, Wood GK, Collie C, Fower A, Fox H, Ellul MA, Held M, Egbe FN, Griffiths M, Solomon T, Breen G, Kipar A, Cavanagh J, Irani SR, Vincent A, Stewart JP, Taams LS, Menon DK, Michael BD. Dunai C, et al. Among authors: fower a. Front Immunol. 2024 Oct 14;15:1440324. doi: 10.3389/fimmu.2024.1440324. eCollection 2024. Front Immunol. 2024. PMID: 39474424 Free PMC article.
Impact of essential genes on the success of genome editing experiments generating 3313 new genetically engineered mouse lines.
Elrick H, Peterson KA, Willis BJ, Lanza DG, Acar EF, Ryder EJ, Teboul L, Kasparek P, Birling MC, Adams DJ, Bradley A, Braun RE, Brown SD, Caulder A, Codner GF, DeMayo FJ, Dickinson ME, Doe B, Duddy G, Gertsenstein M, Goodwin LO, Hérault Y, Lintott LG, Lloyd KCK, Lorenzo I, Mackenzie M, Mallon AM, McKerlie C, Parkinson H, Ramirez-Solis R, Seavitt JR, Sedlacek R, Skarnes WC, Smedley D, Wells S, White JK, Wood JA; International Mouse Phenotyping Consortium; Murray SA, Heaney JD, Nutter LMJ. Elrick H, et al. Sci Rep. 2024 Sep 30;14(1):22626. doi: 10.1038/s41598-024-72418-8. Sci Rep. 2024. PMID: 39349521 Free PMC article.
Author Correction: Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses.
Michael BD, Dunai C, Needham EJ, Tharmaratnam K, Williams R, Huang Y, Boardman SA, Clark JJ, Sharma P, Subramaniam K, Wood GK, Collie C, Digby R, Ren A, Norton E, Leibowitz M, Ebrahimi S, Fower A, Fox H, Tato E, Ellul MA, Sunderland G, Held M, Hetherington C, Egbe FN, Palmos A, Stirrups K, Grundmann A, Chiollaz AC, Sanchez JC, Stewart JP, Griffiths M, Solomon T, Breen G, Coles AJ, Kingston N, Bradley JR, Chinnery PF, Cavanagh J, Irani SR, Vincent A, Baillie JK, Openshaw PJ, Semple MG; ISARIC4C Investigators; COVID-CNS Consortium; Taams LS, Menon DK. Michael BD, et al. Among authors: fower a. Nat Commun. 2024 Apr 4;15(1):2918. doi: 10.1038/s41467-024-47320-6. Nat Commun. 2024. PMID: 38575615 Free PMC article. No abstract available.
Ultrahigh frequencies of peripherally matured LGI1- and CASPR2-reactive B cells characterize the cerebrospinal fluid in autoimmune encephalitis.
Theorell J, Harrison R, Williams R, Raybould MIJ, Zhao M, Fox H, Fower A, Miller G, Wu Z, Browne E, Mgbachi V, Sun B, Mopuri R, Li Y, Waters P, Deane CM, Handel A, Makuch M, Irani SR. Theorell J, et al. Among authors: fower a. Proc Natl Acad Sci U S A. 2024 Feb 13;121(7):e2311049121. doi: 10.1073/pnas.2311049121. Epub 2024 Feb 6. Proc Natl Acad Sci U S A. 2024. PMID: 38319973 Free PMC article.
Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses.
Michael BD, Dunai C, Needham EJ, Tharmaratnam K, Williams R, Huang Y, Boardman SA, Clark JJ, Sharma P, Subramaniam K, Wood GK, Collie C, Digby R, Ren A, Norton E, Leibowitz M, Ebrahimi S, Fower A, Fox H, Tato E, Ellul MA, Sunderland G, Held M, Hetherington C, Egbe FN, Palmos A, Stirrups K, Grundmann A, Chiollaz AC, Sanchez JC, Stewart JP, Griffiths M, Solomon T, Breen G, Coles AJ, Kingston N, Bradley JR, Chinnery PF, Cavanagh J, Irani SR, Vincent A, Baillie JK, Openshaw PJ, Semple MG; ISARIC4C Investigators; COVID-CNS Consortium; Taams LS, Menon DK. Michael BD, et al. Among authors: fower a. Nat Commun. 2023 Dec 22;14(1):8487. doi: 10.1038/s41467-023-42320-4. Nat Commun. 2023. PMID: 38135686 Free PMC article.
Genotyping Genome-Edited Founders and Subsequent Generation.
Mackenzie M, Fower A, Allan AJ, Codner GF, Bunton-Stasyshyn RK, Teboul L. Mackenzie M, et al. Among authors: fower a. Methods Mol Biol. 2023;2631:103-134. doi: 10.1007/978-1-0716-2990-1_4. Methods Mol Biol. 2023. PMID: 36995665
Rituximab abrogates aquaporin-4-specific germinal center activity in patients with neuromyelitis optica spectrum disorders.
Damato V, Theorell J, Al-Diwani A, Kienzler AK, Makuch M, Sun B, Handel A, Akdeniz D, Berretta A, Ramanathan S, Fower A, Whittam D, Gibbons E, McGlashan N, Green E, Huda S, Woodhall M, Palace J, Sheerin F, Waters P, Leite MI, Jacob A, Irani SR. Damato V, et al. Among authors: fower a. Proc Natl Acad Sci U S A. 2022 Jun 14;119(24):e2121804119. doi: 10.1073/pnas.2121804119. Epub 2022 Jun 6. Proc Natl Acad Sci U S A. 2022. PMID: 35666871 Free PMC article.
Naïve B cells followed by aquaporin-4 antibodies characterise the onset of neuromyelitis optica: evidence from stem cell transplantation.
McNaughton P, Payne R, Michael S, Leahy T, Nicols A, Fower A, Hambleton S, Pang K, Gennery A, Irani SR. McNaughton P, et al. Among authors: fower a. J Neurol Neurosurg Psychiatry. 2022 May 23;93(11):1234-6. doi: 10.1136/jnnp-2022-328982. Online ahead of print. J Neurol Neurosurg Psychiatry. 2022. PMID: 35606107 Free PMC article. No abstract available.
Clinical features which predict neuronal surface autoantibodies in new-onset focal epilepsy: implications for immunotherapies.
McGinty RN, Handel A, Moloney T, Ramesh A, Fower A, Torzillo E, Kramer H, Howell S, Waters P, Adcock J, Sen A, Lang B, Irani SR. McGinty RN, et al. Among authors: fower a. J Neurol Neurosurg Psychiatry. 2021 Mar;92(3):291-294. doi: 10.1136/jnnp-2020-325011. Epub 2020 Nov 20. J Neurol Neurosurg Psychiatry. 2021. PMID: 33219046 Free PMC article.