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Extraislet expression of islet antigen boosts T cell exhaustion to partially prevent autoimmune diabetes.
Selck C, Jhala G, De George DJ, Kwong CJ, Christensen MK, Pappas EG, Liu X, Ge T, Trivedi P, Kallies A, Thomas HE, Kay TWH, Krishnamurthy B. Selck C, et al. Among authors: trivedi p. Proc Natl Acad Sci U S A. 2024 Feb 6;121(6):e2315419121. doi: 10.1073/pnas.2315419121. Epub 2024 Jan 29. Proc Natl Acad Sci U S A. 2024. PMID: 38285952 Free PMC article.
Granzyme A Deficiency Breaks Immune Tolerance and Promotes Autoimmune Diabetes Through a Type I Interferon-Dependent Pathway.
Mollah ZUA, Quah HS, Graham KL, Jhala G, Krishnamurthy B, Dharma JFM, Chee J, Trivedi PM, Pappas EG, Mackin L, Chu EPF, Akazawa S, Fynch S, Hodson C, Deans AJ, Trapani JA, Chong MMW, Bird PI, Brodnicki TC, Thomas HE, Kay TWH. Mollah ZUA, et al. Among authors: trivedi pm. Diabetes. 2017 Dec;66(12):3041-3050. doi: 10.2337/db17-0517. Epub 2017 Jul 21. Diabetes. 2017. PMID: 28733313
994 results