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Preclinical Development of CAR T Cells with Antigen-Inducible IL18 Enforcement to Treat GD2-Positive Solid Cancers.
Fischer-Riepe L, Kailayangiri S, Zimmermann K, Pfeifer R, Aigner M, Altvater B, Kretschmann S, Völkl S, Hartley J, Dreger C, Petry K, Bosio A, von Döllen A, Hartmann W, Lode H, Görlich D, Mackensen A, Jungblut M, Schambach A, Abken H, Rossig C. Fischer-Riepe L, et al. Among authors: zimmermann k. Clin Cancer Res. 2024 Aug 15;30(16):3564-3577. doi: 10.1158/1078-0432.CCR-23-3157. Clin Cancer Res. 2024. PMID: 38593230
CAR-Ts redirected against the Thomsen-Friedenreich antigen CD176 mediate specific elimination of malignant cells from leukemia and solid tumors.
Dragon AC, Beermann LM, Umland M, Bonifacius A, Malinconico C, Ruhl L, Kehler P, Gellert J, Weiß L, Mayer-Hain S, Zimmermann K, Riese S, Thol F, Beutel G, Maecker-Kolhoff B, Yamamoto F, Blasczyk R, Schambach A, Hust M, Hudecek M, Eiz-Vesper B. Dragon AC, et al. Among authors: zimmermann k. Front Immunol. 2023 Oct 17;14:1219165. doi: 10.3389/fimmu.2023.1219165. eCollection 2023. Front Immunol. 2023. PMID: 37915564 Free PMC article.
CAR-NK Cells Targeting HER1 (EGFR) Show Efficient Anti-Tumor Activity against Head and Neck Squamous Cell Carcinoma (HNSCC).
Nowak J, Bentele M, Kutle I, Zimmermann K, Lühmann JL, Steinemann D, Kloess S, Koehl U, Roßberg W, Ahmed A, Schaudien D, Neubert L, Kamp JC, Kuehnel MP, Warnecke A, Schambach A, Morgan M. Nowak J, et al. Among authors: zimmermann k. Cancers (Basel). 2023 Jun 13;15(12):3169. doi: 10.3390/cancers15123169. Cancers (Basel). 2023. PMID: 37370779 Free PMC article.
A fluorescent protein C-terminal fusion knock-in is functional with TRPA1 but not TRPC5.
Tragl A, Ptakova A, Sinica V, Meerupally R, König C, Roza C, Barvík I, Vlachova V, Zimmermann K. Tragl A, et al. Among authors: zimmermann k. Biochim Biophys Acta Mol Cell Res. 2024 Dec 9;1872(2):119887. doi: 10.1016/j.bbamcr.2024.119887. Online ahead of print. Biochim Biophys Acta Mol Cell Res. 2024. PMID: 39662746 Free article.
A single-chain variable fragment-based bispecific T-cell activating antibody against CD117 enables T-cell mediated lysis of acute myeloid leukemia and hematopoietic stem and progenitor cells.
Volta L, Myburgh R, Hofstetter M, Koch C, Kiefer JD, Gobbi C, Manfredi F, Zimmermann K, Kaufmann P, Fazio S, Pellegrino C, Russkamp NF, Villars D, Matasci M, Maurer M, Mueller J, Schneiter F, Büschl P, Harrer N, Mock J, Balabanov S, Nombela-Arrieta C, Schroeder T, Neri D, Manz MG. Volta L, et al. Among authors: zimmermann k. Hemasphere. 2024 Nov 19;8(11):e70055. doi: 10.1002/hem3.70055. eCollection 2024 Nov. Hemasphere. 2024. PMID: 39564539 Free PMC article.
Discovery and Preclinical Characterization of Fulacimstat (BAY 1142524), a Potent and Selective Chymase Inhibitor As a New Profibrinolytic Approach for Safe Thrombus Resolution.
Fürstner C, Ackerstaff J, Meier H, Straub A, Mittendorf J, Schamberger J, Schäfer M, Börngen K, Jörißen H, Zubov D, Zimmermann K, Tersteegen A, Geiss V, Hartmann E, Albrecht-Küpper B, D'Orléans-Juste P, Lapointe C, Vincent L, Heitmeier S, Tinel H. Fürstner C, et al. Among authors: zimmermann k. J Med Chem. 2024 Nov 14. doi: 10.1021/acs.jmedchem.4c01819. Online ahead of print. J Med Chem. 2024. PMID: 39541507
The impact of curative cancer treatment on sexual health - clinical results from the EORTC QLQ-SH22 validation study.
Oberguggenberger AS, Engele VI, Schmalz C, Nordin A, Bjelic-Radisic V, Lanceley A, Kuljanic K, Jensen PT, Frøding LP, Creutzberg CL, Zimmermann K, Serpentini S, Arraras JI, Nagele E, Toelen H, Greimel E; EORTC Quality of Life Group. Oberguggenberger AS, et al. Among authors: zimmermann k. BMC Cancer. 2024 Nov 11;24(1):1374. doi: 10.1186/s12885-024-13123-7. BMC Cancer. 2024. PMID: 39523323 Free PMC article.
713 results