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142 results

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Undescribed cytotoxic butenolides; asperterreunolides A-E, isolated from endophytic fungus Aspergillus terreus derived from Artemisia arborescens L. supported with in silico study.
Samy MN, Attia EZ, Khalifa BA, Darwish AG, Al-Karmalawy AA, Alnajjar R, Abdelmosen UR, Ibrahim MA, Ross SA. Samy MN, et al. Among authors: al karmalawy aa. Phytochemistry. 2024 Dec 30;232:114377. doi: 10.1016/j.phytochem.2024.114377. Online ahead of print. Phytochemistry. 2024. PMID: 39743005
Cognitive-enhancing effect of Cordia dichotoma fruit on scopolamine-induced cognitive impairment in rats: metabolite profiling, in vivo, and in silico investigations.
Hussein HM, Abdel Kawy MA, Eltanany BM, Pont L, Benavente F, Fayez AM, Alnajjar R, Al-Karmalawy AA, Abdelmonem AR, Mohsen E. Hussein HM, et al. Among authors: al karmalawy aa. RSC Adv. 2024 Dec 23;14(54):40267-40286. doi: 10.1039/d4ra06991a. eCollection 2024 Dec 17. RSC Adv. 2024. PMID: 39717818 Free PMC article.
Biological and computational assessments of thiazole derivative-reinforced bile salt enriched nano carriers: a new gate in targeting SARS-CoV-2 spike protein.
Zakaria MY, Elmaaty AA, El-Shesheny R, Alnajjar R, Kutkat O, Ben Moussa S, Abdullah Alzahrani AY, El-Zahaby SA, Al-Karmalawy AA. Zakaria MY, et al. Among authors: al karmalawy aa. RSC Adv. 2024 Dec 9;14(52):38778-38795. doi: 10.1039/d4ra07316a. eCollection 2024 Dec 3. RSC Adv. 2024. PMID: 39654925 Free PMC article.
Dabigatran attenuates methotrexate-induced hepatotoxicity by regulating coagulation, endothelial dysfunction, and the NF-kB/IL-1β/MCP-1 and TLR4/NLRP3 signaling pathways.
El-Dessouki AM, Alzokaky AA, Raslan NA, Ibrahim S, Selim HMRM, Al-Karmalawy AA. El-Dessouki AM, et al. Among authors: al karmalawy aa. Naunyn Schmiedebergs Arch Pharmacol. 2024 Nov 11. doi: 10.1007/s00210-024-03567-w. Online ahead of print. Naunyn Schmiedebergs Arch Pharmacol. 2024. PMID: 39527308
Investigating the anti-inflammatory potential of N-amidic acid organoselenium candidates: biological assessments, molecular docking, and molecular dynamics simulations.
Althikrallah HA, Shaaban S, Elmaaty AA, Ba-Ghazal H, Almarri MN, Sharaky M, Alnajjar R, Al-Karmalawy AA. Althikrallah HA, et al. Among authors: al karmalawy aa. RSC Adv. 2024 Oct 9;14(44):31990-32000. doi: 10.1039/d4ra04762a. eCollection 2024 Oct 9. RSC Adv. 2024. PMID: 39391620 Free PMC article.
Muti-target rationale design of novel substituted N-phenyl-2-((6-phenylpyridazin-3-yl)thio)acetamide candidates as telomerase/JAK1/STAT3/TLR4 inhibitors: In vitro and in vivo investigations.
Shaldam MA, Mousa MHA, Tawfik HO, El-Dessouki AM, Sharaky M, Saleh MM, Alzahrani AYA, Moussa SB, Al-Karmalawy AA. Shaldam MA, et al. Among authors: al karmalawy aa. Bioorg Chem. 2024 Dec;153:107843. doi: 10.1016/j.bioorg.2024.107843. Epub 2024 Sep 24. Bioorg Chem. 2024. PMID: 39332072
142 results