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A comprehensive single-cell breast tumor atlas defines epithelial and immune heterogeneity and interactions predicting anti-PD-1 therapy response.
Xu L, Saunders K, Huang SP, Knutsdottir H, Martinez-Algarin K, Terrazas I, Chen K, McArthur HM, Maués J, Hodgdon C, Reddy SM, Roussos Torres ET, Xu L, Chan IS. Xu L, et al. Among authors: martinez algarin k. Cell Rep Med. 2024 May 21;5(5):101511. doi: 10.1016/j.xcrm.2024.101511. Epub 2024 Apr 12. Cell Rep Med. 2024. PMID: 38614094 Free PMC article.
Organoid generation from mouse mammary tumors captures the genetic heterogeneity of clinically relevant copy number alterations.
Lake KE, Colonetta MM, Smith CA, Martinez-Algarin K, Saunders K, Mohta S, Pena J, McArthur HL, Reddy SM, Roussos-Torres ET, Chen EH, Chan IS. Lake KE, et al. Among authors: martinez algarin k. bioRxiv [Preprint]. 2023 Jan 31:2023.01.29.526141. doi: 10.1101/2023.01.29.526141. bioRxiv. 2023. PMID: 36778256 Free PMC article. Preprint.
Digital droplet PCR analysis of organoids generated from mouse mammary tumors demonstrates proof-of-concept capture of tumor heterogeneity.
Lake KE, Colonnetta MM, Smith CA, Saunders K, Martinez-Algarin K, Mohta S, Pena J, McArthur HL, Reddy SM, Roussos Torres ET, Chen EH, Chan IS. Lake KE, et al. Among authors: martinez algarin k. Front Cell Dev Biol. 2024 May 15;12:1358583. doi: 10.3389/fcell.2024.1358583. eCollection 2024. Front Cell Dev Biol. 2024. PMID: 38827528 Free PMC article.