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Suppression of tau propagation using an inhibitor that targets the DK-switch of nSMase2.
Bilousova T, Elias C, Miyoshi E, Alam MP, Zhu C, Campagna J, Vadivel K, Jagodzinska B, Gylys KH, John V. Bilousova T, et al. Among authors: miyoshi e. Biochem Biophys Res Commun. 2018 May 23;499(4):751-757. doi: 10.1016/j.bbrc.2018.03.209. Epub 2018 Apr 9. Biochem Biophys Res Commun. 2018. PMID: 29604274 Free PMC article.
Apolipoprotein E/Amyloid-β Complex Accumulates in Alzheimer Disease Cortical Synapses via Apolipoprotein E Receptors and Is Enhanced by APOE4.
Bilousova T, Melnik M, Miyoshi E, Gonzalez BL, Poon WW, Vinters HV, Miller CA, Corrada MM, Kawas C, Hatami A, Albay R 3rd, Glabe C, Gylys KH. Bilousova T, et al. Among authors: miyoshi e. Am J Pathol. 2019 Aug;189(8):1621-1636. doi: 10.1016/j.ajpath.2019.04.010. Epub 2019 May 17. Am J Pathol. 2019. PMID: 31108099 Free PMC article.
Exosomal tau with seeding activity is released from Alzheimer's disease synapses, and seeding potential is associated with amyloid beta.
Miyoshi E, Bilousova T, Melnik M, Fakhrutdinov D, Poon WW, Vinters HV, Miller CA, Corrada M, Kawas C, Bohannan R, Caraway C, Elias C, Maina KN, Campagna JJ, John V, Gylys KH. Miyoshi E, et al. Lab Invest. 2021 Dec;101(12):1605-1617. doi: 10.1038/s41374-021-00644-z. Epub 2021 Aug 30. Lab Invest. 2021. PMID: 34462532 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 39750969
Spatial and single-nucleus transcriptomic analysis of genetic and sporadic forms of Alzheimer's Disease.
Miyoshi E, Morabito S, Henningfield CM, Rahimzadeh N, Kiani Shabestari S, Das S, Michael N, Reese F, Shi Z, Cao Z, Scarfone V, Arreola MA, Lu J, Wright S, Silva J, Leavy K, Lott IT, Doran E, Yong WH, Shahin S, Perez-Rosendahl M, Head E, Green KN, Swarup V. Miyoshi E, et al. bioRxiv [Preprint]. 2023 Jul 26:2023.07.24.550282. doi: 10.1101/2023.07.24.550282. bioRxiv. 2023. Update in: Nat Genet. 2024 Dec;56(12):2704-2717. doi: 10.1038/s41588-024-01961-x PMID: 37546983 Free PMC article. Updated. Preprint.
395 results