β-lactamase inhibitors display anti-seizure properties in an invertebrate assay.
Rawls SM, Karaca F, Madhani I, Bhojani V, Martinez RL, Abou-Gharbia M, Raffa RB.
Rawls SM, et al.
Neuroscience. 2010 Sep 15;169(4):1800-4. doi: 10.1016/j.neuroscience.2010.06.041. Epub 2010 Jun 23.
Neuroscience. 2010.
PMID: 20600649
Free PMC article.
We hypothesized that the structurally related beta-lactamase inhibitors (clavulanic acid, tazobactam)--which also contain a beta-lactam ring--will mimic ceftriaxone efficacy in an invertebrate (planarian) assay designed to screen for anti-seizure activity [Rawls SM, …
We hypothesized that the structurally related beta-lactamase inhibitors (clavulanic acid, tazobactam)--which also contain a beta-lactam ring …