Freddolino PL - Search Results

1

Regulation of the Drosophila transcriptome by Pumilio and the CCR4-NOT deadenylase complex.

Haugen RJ, Barnier C, Elrod ND, Luo H, Jensen MK, Ji P, Smibert CA, Lipshitz HD, Wagner EJ, Freddolino PL, Goldstrohm AC. Haugen RJ, et al. Among authors: freddolino pl. RNA. 2024 Jun 17;30(7):866-890. doi: 10.1261/rna.079813.123. RNA. 2024. PMID: 38627019

2

Principles of mRNA control by human PUM proteins elucidated from multimodal experiments and integrative data analysis.

Wolfe MB, Schagat TL, Paulsen MT, Magnuson B, Ljungman M, Park D, Zhang C, Campbell ZT, Goldstrohm AC, Freddolino PL. Wolfe MB, et al. Among authors: freddolino pl. RNA. 2020 Nov;26(11):1680-1703. doi: 10.1261/rna.077362.120. Epub 2020 Aug 4. RNA. 2020. PMID: 32753408 Free PMC article.

3

Global analysis of RNA metabolism using bio-orthogonal labeling coupled with next-generation RNA sequencing.

Wolfe MB, Goldstrohm AC, Freddolino PL. Wolfe MB, et al. Among authors: freddolino pl. Methods. 2019 Feb 15;155:88-103. doi: 10.1016/j.ymeth.2018.12.001. Epub 2018 Dec 6. Methods. 2019. PMID: 30529548 Free PMC article. Review.

4

Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins.

Bohn JA, Van Etten JL, Schagat TL, Bowman BM, McEachin RC, Freddolino PL, Goldstrohm AC. Bohn JA, et al. Among authors: freddolino pl. Nucleic Acids Res. 2018 Jan 9;46(1):362-386. doi: 10.1093/nar/gkx1120. Nucleic Acids Res. 2018. PMID: 29165587 Free PMC article.

5

Unique repression domains of Pumilio utilize deadenylation and decapping factors to accelerate destruction of target mRNAs.

Arvola RM, Chang CT, Buytendorp JP, Levdansky Y, Valkov E, Freddolino PL, Goldstrohm AC. Arvola RM, et al. Among authors: freddolino pl. Nucleic Acids Res. 2020 Feb 28;48(4):1843-1871. doi: 10.1093/nar/gkz1187. Nucleic Acids Res. 2020. PMID: 31863588 Free PMC article.

6

Differential processing and localization of human Nocturnin controls metabolism of mRNA and nicotinamide adenine dinucleotide cofactors.

Abshire ET, Hughes KL, Diao R, Pearce S, Gopalakrishna S, Trievel RC, Rorbach J, Freddolino PL, Goldstrohm AC. Abshire ET, et al. Among authors: freddolino pl. J Biol Chem. 2020 Oct 30;295(44):15112-15133. doi: 10.1074/jbc.RA120.012618. Epub 2020 Aug 23. J Biol Chem. 2020. PMID: 32839274 Free PMC article.

7

The structure of human Nocturnin reveals a conserved ribonuclease domain that represses target transcript translation and abundance in cells.

Abshire ET, Chasseur J, Bohn JA, Del Rizzo PA, Freddolino PL, Goldstrohm AC, Trievel RC. Abshire ET, et al. Among authors: freddolino pl. Nucleic Acids Res. 2018 Jul 6;46(12):6257-6270. doi: 10.1093/nar/gky412. Nucleic Acids Res. 2018. PMID: 29860338 Free PMC article.

8

A Well-Mixed E. coli Genome: Widespread Contacts Revealed by Tracking Mu Transposition.

Walker DM, Freddolino PL, Harshey RM. Walker DM, et al. Among authors: freddolino pl. Cell. 2020 Feb 20;180(4):703-716.e18. doi: 10.1016/j.cell.2020.01.031. Epub 2020 Feb 13. Cell. 2020. PMID: 32059782 Free PMC article.

9

Uncovering Transcriptional Regulators and Targets of sRNAs Using an Integrative Data-Mining Approach: H-NS-Regulated RseX as a Case Study.

Mihailovic MK, Ekdahl AM, Chen A, Leistra AN, Li B, González Martínez J, Law M, Ejindu C, Massé É, Freddolino PL, Contreras LM. Mihailovic MK, et al. Among authors: freddolino pl. Front Cell Infect Microbiol. 2021 Jul 13;11:696533. doi: 10.3389/fcimb.2021.696533. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 34327153 Free PMC article.

10

Escherichia coli Leucine-Responsive Regulatory Protein Bridges DNA In Vivo and Tunably Dissociates in the Presence of Exogenous Leucine.

Ziegler CA, Freddolino PL. Ziegler CA, et al. Among authors: freddolino pl. mBio. 2023 Apr 25;14(2):e0269022. doi: 10.1128/mbio.02690-22. Epub 2023 Feb 14. mBio. 2023. PMID: 36786566 Free PMC article.

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