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Simultaneous deletion of ghrelin and its receptor increases motor activity and energy expenditure.
Pfluger PT, Kirchner H, Günnel S, Schrott B, Perez-Tilve D, Fu S, Benoit SC, Horvath T, Joost HG, Wortley KE, Sleeman MW, Tschöp MH. Pfluger PT, et al. Among authors: wortley ke. Am J Physiol Gastrointest Liver Physiol. 2008 Mar;294(3):G610-8. doi: 10.1152/ajpgi.00321.2007. Epub 2007 Nov 29. Am J Physiol Gastrointest Liver Physiol. 2008. PMID: 18048479 Free article.
Peptide YY regulates bone turnover in rodents.
Wortley KE, Garcia K, Okamoto H, Thabet K, Anderson KD, Shen V, Herman JP, Valenzuela D, Yancopoulos GD, Tschöp MH, Murphy A, Sleeman MW. Wortley KE, et al. Gastroenterology. 2007 Nov;133(5):1534-43. doi: 10.1053/j.gastro.2007.08.024. Epub 2007 Aug 15. Gastroenterology. 2007. PMID: 17920065
Absence of ghrelin protects against early-onset obesity.
Wortley KE, del Rincon JP, Murray JD, Garcia K, Iida K, Thorner MO, Sleeman MW. Wortley KE, et al. J Clin Invest. 2005 Dec;115(12):3573-8. doi: 10.1172/JCI26003. J Clin Invest. 2005. PMID: 16322795 Free PMC article.
Resistance to diet-induced obesity in mice globally overexpressing OGH/GPB5.
Macdonald LE, Wortley KE, Gowen LC, Anderson KD, Murray JD, Poueymirou WT, Simmons MV, Barber D, Valenzuela DM, Economides AN, Wiegand SJ, Yancopoulos GD, Sleeman MW, Murphy AJ. Macdonald LE, et al. Among authors: wortley ke. Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2496-501. doi: 10.1073/pnas.0409849102. Epub 2005 Feb 7. Proc Natl Acad Sci U S A. 2005. PMID: 15699348 Free PMC article.
16 results