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Page 1
Gene Therapy for High Grade Glioma: The Clinical Experience.
Varela ML, Comba A, Faisal SM, Argento A, Franson A, Barissi MN, Sachdev S, Castro MG, Lowenstein PR. Varela ML, et al. Expert Opin Biol Ther. 2023 Feb;23(2):145-161. doi: 10.1080/14712598.2022.2157718. Epub 2022 Dec 16. Expert Opin Biol Ther. 2023. PMID: 36510843 Free PMC article. Review.
Generation of 3D ex vivo mouse- and patient-derived glioma explant slice model for integration of confocal time-lapse imaging and spatial analysis.
Comba A, Varela ML, Faisal SM, Abel CC 2nd, Argento AE, Al-Holou WN, Hollon TC, Perelman JD, Dunn PJ, Motsch S, Castro MG, Lowenstein PR. Comba A, et al. Among authors: varela ml. STAR Protoc. 2023 Mar 16;4(2):102174. doi: 10.1016/j.xpro.2023.102174. Online ahead of print. STAR Protoc. 2023. PMID: 36930648 Free PMC article.
Combined cytotoxic and immune-stimulatory gene therapy for primary adult high-grade glioma: a phase 1, first-in-human trial.
Umemura Y, Orringer D, Junck L, Varela ML, West MEJ, Faisal SM, Comba A, Heth J, Sagher O, Leung D, Mammoser A, Hervey-Jumper S, Zamler D, Yadav VN, Dunn P, Al-Holou W, Hollon T, Kim MM, Wahl DR, Camelo-Piragua S, Lieberman AP, Venneti S, McKeever P, Lawrence T, Kurokawa R, Sagher K, Altshuler D, Zhao L, Muraszko K, Castro MG, Lowenstein PR. Umemura Y, et al. Among authors: varela ml. Lancet Oncol. 2023 Sep;24(9):1042-1052. doi: 10.1016/S1470-2045(23)00347-9. Lancet Oncol. 2023. PMID: 37657463 Clinical Trial.
Cell and gene therapy in neuro-oncology.
Varela ML, Comba A, Faisal SM, Argento A, Peña Aguelo JA, Candolfi M, Castro MG, Lowenstein PR. Varela ML, et al. Handb Clin Neurol. 2024;205:297-315. doi: 10.1016/B978-0-323-90120-8.00009-5. Handb Clin Neurol. 2024. PMID: 39341660 Free PMC article. Review.
Zinc Finger MYND-Type Containing 8 (ZMYND8) Is Epigenetically Regulated in Mutant Isocitrate Dehydrogenase 1 (IDH1) Glioma to Promote Radioresistance.
Carney SV, Banerjee K, Mujeeb A, Zhu B, Haase S, Varela ML, Kadiyala P, Tronrud CE, Zhu Z, Mukherji D, Gorla P, Sun Y, Tagett R, Núñez FJ, Luo M, Luo W, Ljungman M, Liu Y, Xia Z, Schwendeman A, Qin T, Sartor MA, Costello JF, Cahill DP, Lowenstein PR, Castro MG. Carney SV, et al. Among authors: varela ml. Clin Cancer Res. 2023 May 1;29(9):1763-1782. doi: 10.1158/1078-0432.CCR-22-1896. Clin Cancer Res. 2023. PMID: 36692427 Free PMC article.
51 results