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Expanding the Chemical Space of Transforming Growth Factor-β (TGFβ) Receptor Type II Degraders with 3,4-Disubstituted Indole Derivatives.
Längle D, Wojtowicz-Piotrowski S, Priegann T, Keller N, Wesseler F, Reckzeh ES, Steffens K, Grathwol C, Lemke J, Flasshoff M, Näther C, Jonson AC, Link A, Koch O, Di Guglielmo GM, Schade D. Längle D, et al. Among authors: grathwol c. ACS Pharmacol Transl Sci. 2024 Mar 21;7(4):1069-1085. doi: 10.1021/acsptsci.3c00371. eCollection 2024 Apr 12. ACS Pharmacol Transl Sci. 2024. PMID: 38633593
Practical synthesis and biological screening of sulfonyl hydrazides.
Macara J, Caldeira C, Cunha J, Coelho JAS, Silva MJSA, Krämer K, Grathwol CW, Bräse S, Marques MMB. Macara J, et al. Among authors: grathwol cw. Org Biomol Chem. 2023 Mar 8;21(10):2118-2126. doi: 10.1039/d2ob02160a. Org Biomol Chem. 2023. PMID: 36606485
Correlation Analysis of Protein Expression of 10 HDAC/Sirtuin Isoenzymes with Sensitivities of 23 Anticancer Drugs in 17 Cancer Cell Lines and Potentiation of Drug Activity by Co-Treatment with HDAC Inhibitors.
Behnisch-Cornwell S, Grathwol CW, Schulig L, Voigt A, Baecker D, Link A, Bednarski PJ. Behnisch-Cornwell S, et al. Among authors: grathwol cw. Cancers (Basel). 2021 Dec 31;14(1):187. doi: 10.3390/cancers14010187. Cancers (Basel). 2021. PMID: 35008351 Free PMC article.
Engineering Regioselectivity of a P450 Monooxygenase Enables the Synthesis of Ursodeoxycholic Acid via 7β-Hydroxylation of Lithocholic Acid.
Grobe S, Badenhorst CPS, Bayer T, Hamnevik E, Wu S, Grathwol CW, Link A, Koban S, Brundiek H, Großjohann B, Bornscheuer UT. Grobe S, et al. Among authors: grathwol cw. Angew Chem Int Ed Engl. 2021 Jan 11;60(2):753-757. doi: 10.1002/anie.202012675. Epub 2020 Nov 12. Angew Chem Int Ed Engl. 2021. PMID: 33085147 Free PMC article.
13 results