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A global to local genomics analysis of Clostridioides difficile ST1/RT027 identifies cryptic transmission events in a northern Arizona healthcare network.
Williamson CHD, Stone NE, Nunnally AE, Hornstra HM, Wagner DM, Roe CC, Vazquez AJ, Nandurkar N, Vinocur J, Terriquez J, Gillece J, Travis J, Lemmer D, Keim P, Sahl JW. Williamson CHD, et al. Among authors: nunnally ae. Microb Genom. 2019 Jul;5(7):e000271. doi: 10.1099/mgen.0.000271. Epub 2019 May 20. Microb Genom. 2019. PMID: 31107202 Free PMC article.
A local-scale One Health genomic surveillance of Clostridioides difficile demonstrates highly related strains from humans, canines, and the environment.
Williamson CHD, Roe CC, Terriquez J, Hornstra H, Lucero S, Nunnally AE, Vazquez AJ, Vinocur J, Plude C, Nienstadt L, Stone NE, Celona KR, Wagner DM, Keim P, Sahl JW. Williamson CHD, et al. Among authors: nunnally ae. Microb Genom. 2023 Jun;9(6):mgen001046. doi: 10.1099/mgen.0.001046. Microb Genom. 2023. PMID: 37347682 Free PMC article.
Domestic canines do not display evidence of gut microbial dysbiosis in the presence of Clostridioides (Clostridium) difficile, despite cellular susceptibility to its toxins.
Stone NE, Nunnally AE, Jimenez V Jr, Cope EK, Sahl JW, Sheridan K, Hornstra HM, Vinocur J, Settles EW, Headley KC, Williamson CHD, Rideout JR, Bolyen E, Caporaso JG, Terriquez J, Monroy FP, Busch JD, Keim P, Wagner DM. Stone NE, et al. Among authors: nunnally ae. Anaerobe. 2019 Aug;58:53-72. doi: 10.1016/j.anaerobe.2019.03.017. Epub 2019 Apr 1. Anaerobe. 2019. PMID: 30946985 Free article.