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528 results

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Page 1
B cell immunofocusing and repriming in two HIV-1 Env immunization regimens.
DeLuca JM, Blasi M, Jha S, Shen X, Pollara J, Kerkau M, Purwar M, Carnathan DG, Negri D, Cara A, Wollenberg K, Saunders KO, Lu S, Silvestri G, Weiner DB, Klotman ME, Ferrari G, Moody MA, Bonsignori M. DeLuca JM, et al. Among authors: weiner db. Res Sq [Preprint]. 2024 Apr 8:rs.3.rs-3895128. doi: 10.21203/rs.3.rs-3895128/v1. Res Sq. 2024. PMID: 38659814 Free PMC article. Preprint.
Personalized neoantigen vaccine and pembrolizumab in advanced hepatocellular carcinoma: a phase 1/2 trial.
Yarchoan M, Gane EJ, Marron TU, Perales-Linares R, Yan J, Cooch N, Shu DH, Fertig EJ, Kagohara LT, Bartha G, Northcott J, Lyle J, Rochestie S, Peters J, Connor JT, Jaffee EM, Csiki I, Weiner DB, Perales-Puchalt A, Sardesai NY. Yarchoan M, et al. Among authors: weiner db. Nat Med. 2024 Apr;30(4):1044-1053. doi: 10.1038/s41591-024-02894-y. Epub 2024 Apr 7. Nat Med. 2024. PMID: 38584166 Free PMC article. Clinical Trial.
In vivo delivery of engineered synthetic DNA-encoded SARS-CoV-2 monoclonal antibodies for pre-exposure prophylaxis in non-human primates.
Patel A, Rosenke K, Parzych EM, Feldmann F, Bharti S, Griffin AJ, Schouest B, Lewis M, Choi J, Chokkalingam N, Machado V, Smith BJ, Frase D, Ali AR, Lovaglio J, Nguyen B, Hanley PW, Walker SN, Gary EN, Kulkarni A, Generotti A, Francica JR, Rosenthal K, Kulp DW, Esser MT, Smith TRF, Shaia C, Weiner DB, Feldmann H. Patel A, et al. Among authors: weiner db. Emerg Microbes Infect. 2024 Dec;13(1):2294860. doi: 10.1080/22221751.2023.2294860. Epub 2024 Feb 28. Emerg Microbes Infect. 2024. PMID: 38165394 Free PMC article.
Siglec-7 glyco-immune binding mAbs or NK cell engager biologics induce potent antitumor immunity against ovarian cancers.
Bordoloi D, Kulkarni AJ, Adeniji OS, Pampena MB, Bhojnagarwala PS, Zhao S, Ionescu C, Perales-Puchalt A, Parzych EM, Zhu X, Ali AR, Cassel J, Zhang R, Betts MR, Abdel-Mohsen M, Weiner DB. Bordoloi D, et al. Among authors: weiner db. Sci Adv. 2023 Nov 3;9(44):eadh4379. doi: 10.1126/sciadv.adh4379. Epub 2023 Nov 1. Sci Adv. 2023. PMID: 37910620 Free PMC article.
Irreversible Inactivation of SARS-CoV-2 by Lectin Engagement with Two Glycan Clusters on the Spike Protein.
Nangarlia A, Hassen FF, Canziani G, Bandi P, Talukder C, Zhang F, Krauth D, Gary EN, Weiner DB, Bieniasz P, Navas-Martin S, O'Keefe BR, Ang CG, Chaiken I. Nangarlia A, et al. Among authors: weiner db. Biochemistry. 2023 Jul 18;62(14):2115-2127. doi: 10.1021/acs.biochem.3c00109. Epub 2023 Jun 21. Biochemistry. 2023. PMID: 37341186 Free PMC article.
Delivery platforms for broadly neutralizing antibodies.
Joshi LR, Gálvez NMS, Ghosh S, Weiner DB, Balazs AB. Joshi LR, et al. Among authors: weiner db. Curr Opin HIV AIDS. 2023 Jul 1;18(4):191-208. doi: 10.1097/COH.0000000000000803. Epub 2023 May 15. Curr Opin HIV AIDS. 2023. PMID: 37265268 Free PMC article. Review.
Adenosine deaminase augments SARS-CoV-2 specific cellular and humoral responses in aged mouse models of immunization and challenge.
Gary EN, Tursi NJ, Warner BM, Cuismano G, Connors J, Parzych EM, Griffin BD, Bell MR, Ali AR, Frase D, Hojecki CE, Canziani GA, Chaiken I, Kannan T, Moffat E, Embury-Hyatt C, Wooton SK, Kossenkov A, Patel A, Kobasa D, Kutzler MA, Haddad EK, Weiner DB. Gary EN, et al. Among authors: weiner db. Front Immunol. 2023 Mar 14;14:1138609. doi: 10.3389/fimmu.2023.1138609. eCollection 2023. Front Immunol. 2023. PMID: 36999023 Free PMC article.
Multivalent in vivo delivery of DNA-encoded bispecific T cell engagers effectively controls heterogeneous GBM tumors and mitigates immune escape.
Park DH, Liaw K, Bhojnagarwala P, Zhu X, Choi J, Ali AR, Bordoloi D, Gary EN, O'Connell RP, Kulkarni A, Guimet D, Smith T, Perales-Puchalt A, Patel A, Weiner DB. Park DH, et al. Among authors: weiner db. Mol Ther Oncolytics. 2023 Feb 16;28:249-263. doi: 10.1016/j.omto.2023.02.004. eCollection 2023 Mar 16. Mol Ther Oncolytics. 2023. PMID: 36915911 Free PMC article.
Engineered antibody cytokine chimera synergizes with DNA-launched nanoparticle vaccines to potentiate melanoma suppression in vivo.
Tursi NJ, Xu Z, Helble M, Walker S, Liaw K, Chokkalingam N, Kannan T, Wu Y, Tello-Ruiz E, Park DH, Zhu X, Wise MC, Smith TRF, Majumdar S, Kossenkov A, Kulp DW, Weiner DB. Tursi NJ, et al. Among authors: weiner db. Front Immunol. 2023 Feb 23;14:1072810. doi: 10.3389/fimmu.2023.1072810. eCollection 2023. Front Immunol. 2023. PMID: 36911698 Free PMC article.
528 results