Aggarwal P - Search Results

1

Transcriptional Variabilities in Human hiPSC-derived Cardiomyocytes: All Genes Are Not Equal and Their Robustness May Foretell Donor's Disease Susceptibility.

Gu CC, Matter A, Turner A, Aggarwal P, Yang W, Sun X, Hunt SC, Lewis CE, Arnett DK, Anson B, Kattman S, Broeckel U. Gu CC, et al. Among authors: aggarwal p. bioRxiv [Preprint]. 2024 Apr 21:2024.04.18.584138. doi: 10.1101/2024.04.18.584138. bioRxiv. 2024. PMID: 38659937 Free PMC article. Preprint.

2

RNA expression profiling of human iPSC-derived cardiomyocytes in a cardiac hypertrophy model.

Aggarwal P, Turner A, Matter A, Kattman SJ, Stoddard A, Lorier R, Swanson BJ, Arnett DK, Broeckel U. Aggarwal P, et al. PLoS One. 2014 Sep 25;9(9):e108051. doi: 10.1371/journal.pone.0108051. eCollection 2014. PLoS One. 2014. PMID: 25255322 Free PMC article.

3

The introduction of RNA-DNA differences underlies interindividual variation in the human IL12RB1 mRNA repertoire.

Turner AJ, Aggarwal P, Miller HE, Waukau J, Routes JM, Broeckel U, Robinson RT. Turner AJ, et al. Among authors: aggarwal p. Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):15414-9. doi: 10.1073/pnas.1515978112. Epub 2015 Nov 30. Proc Natl Acad Sci U S A. 2015. PMID: 26621740 Free PMC article.

4

Comprehensive evaluation of AmpliSeq transcriptome, a novel targeted whole transcriptome RNA sequencing methodology for global gene expression analysis.

Li W, Turner A, Aggarwal P, Matter A, Storvick E, Arnett DK, Broeckel U. Li W, et al. Among authors: aggarwal p. BMC Genomics. 2015 Dec 16;16:1069. doi: 10.1186/s12864-015-2270-1. BMC Genomics. 2015. PMID: 26673413 Free PMC article.

5

Human IL12RB1 expression is allele-biased and produces a novel IL12 response regulator.

Reeme AE, Claeys TA, Aggarwal P, Turner AJ, Routes JM, Broeckel U, Robinson RT. Reeme AE, et al. Among authors: aggarwal p. Genes Immun. 2019 Mar;20(3):181-197. doi: 10.1038/s41435-018-0023-2. Epub 2018 Mar 30. Genes Immun. 2019. PMID: 29599514 Free PMC article.

6

Donor-specific phenotypic variation in hiPSC cardiomyocyte-derived exosomes impacts endothelial cell function.

Turner A, Aggarwal P, Matter A, Olson B, Gu CC, Hunt SC, Lewis CE, Arnett DK, Lorier R, Broeckel U. Turner A, et al. Among authors: aggarwal p. Am J Physiol Heart Circ Physiol. 2021 Mar 1;320(3):H954-H968. doi: 10.1152/ajpheart.00463.2020. Epub 2021 Jan 8. Am J Physiol Heart Circ Physiol. 2021. PMID: 33416449 Free PMC article.

7

Whole-Exome Sequencing and hiPSC Cardiomyocyte Models Identify MYRIP, TRAPPC11, and SLC27A6 of Potential Importance to Left Ventricular Hypertrophy in an African Ancestry Population.

Irvin MR, Aggarwal P, Claas SA, de las Fuentes L, Do AN, Gu CC, Matter A, Olson BS, Patki A, Schwander K, Smith JD, Srinivasasainagendra V, Tiwari HK, Turner AJ, Nickerson DA, Rao DC, Broeckel U, Arnett DK. Irvin MR, et al. Among authors: aggarwal p. Front Genet. 2021 Feb 19;12:588452. doi: 10.3389/fgene.2021.588452. eCollection 2021. Front Genet. 2021. PMID: 33679876 Free PMC article.

8

Enhancing the functional maturity of hiPSC-derived cardiomyocytes to assess inotropic compounds.

Zhang X, Aggarwal P, Broeckel U, Abassi YA. Zhang X, et al. Among authors: aggarwal p. J Pharmacol Toxicol Methods. 2023 Sep-Oct;123:107282. doi: 10.1016/j.vascn.2023.107282. Epub 2023 Jul 6. J Pharmacol Toxicol Methods. 2023. PMID: 37419294

9

Predicting oncology drug-induced cardiotoxicity with donor-specific iPSC-CMs-a proof-of-concept study with doxorubicin.

Pang L, Cai C, Aggarwal P, Wang D, Vijay V, Bagam P, Blamer J, Matter A, Turner A, Ren L, Papineau K, Srinivasasainagendra V, Tiwari HK, Yang X, Schnackenberg L, Mattes W, Broeckel U. Pang L, et al. Among authors: aggarwal p. Toxicol Sci. 2024 Jun 26;200(1):79-94. doi: 10.1093/toxsci/kfae041. Toxicol Sci. 2024. PMID: 38547396 Free PMC article.

10

IL-10 produced by induced regulatory T cells (iTregs) controls colitis and pathogenic ex-iTregs during immunotherapy.

Schmitt EG, Haribhai D, Williams JB, Aggarwal P, Jia S, Charbonnier LM, Yan K, Lorier R, Turner A, Ziegelbauer J, Georgiev P, Simpson P, Salzman NH, Hessner MJ, Broeckel U, Chatila TA, Williams CB. Schmitt EG, et al. Among authors: aggarwal p. J Immunol. 2012 Dec 15;189(12):5638-48. doi: 10.4049/jimmunol.1200936. Epub 2012 Nov 2. J Immunol. 2012. PMID: 23125413 Free PMC article.

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