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Integrated omics analysis unveils a DNA damage response to neurogenic injury.
Gheinani AH, Sack BS, Bigger-Allen A, Thaker H, Atta H, Lambrinos G, Costa K, Doyle C, Gharaee-Kermani M, Patalano S, Piper M, Cotellessa JF, Vitko D, Li H, Prabhakaran MK, Cristofaro V, Froehlich J, Lee RS, Yang W, Sullivan MP, Macoska JA, Adam RM. Gheinani AH, et al. Among authors: yang w. bioRxiv [Preprint]. 2023 Dec 10:2023.12.10.571015. doi: 10.1101/2023.12.10.571015. bioRxiv. 2023. PMID: 38106029 Free PMC article. Preprint.
Diffusing protein binders to intrinsically disordered proteins.
Liu C, Wu K, Choi H, Han H, Zhang X, Watson JL, Shijo S, Bera AK, Kang A, Brackenbrough E, Coventry B, Hick DR, Hoofnagle AN, Zhu P, Li X, Decarreau J, Gerben SR, Yang W, Wang X, Lamp M, Murray A, Bauer M, Baker D. Liu C, et al. Among authors: yang w. bioRxiv [Preprint]. 2024 Jul 16:2024.07.16.603789. doi: 10.1101/2024.07.16.603789. bioRxiv. 2024. PMID: 39071267 Free PMC article. Preprint.
Extracellular Vesicles heterogeneity through the lens of multiomics.
Silva TF, Hutchins E, Zhao W, Ciani Y, Kim M, Mariscal J, Qiu Z, Kittel A, Zhou B, Wang Y, Hall M, Galasso F, Reiman R, Freeman MR, Parker S, Van Eyk J, Yang W, Posadas E, Guarnerio J, Nolan J, Thery C, Zijlstra A, Stott S, You S, Demichelis F, Boutros P, Van Keuren-Jensen K, Di Vizio D. Silva TF, et al. Among authors: yang w. bioRxiv [Preprint]. 2024 Aug 19:2024.08.14.607999. doi: 10.1101/2024.08.14.607999. bioRxiv. 2024. PMID: 39229160 Free PMC article. Preprint.
Design of High Affinity Binders to Convex Protein Target Sites.
Yang W, Hicks DR, Ghosh A, Schwartze TA, Conventry B, Goreshnik I, Allen A, Halabiya SF, Kim CJ, Hinck CS, Lee DS, Bera AK, Li Z, Wang Y, Schlichthaerle T, Cao L, Huang B, Garrett S, Gerben SR, Rettie S, Heine P, Murray A, Edman N, Carter L, Stewart L, Almo S, Hinck AP, Baker D. Yang W, et al. bioRxiv [Preprint]. 2024 May 2:2024.05.01.592114. doi: 10.1101/2024.05.01.592114. bioRxiv. 2024. PMID: 38746206 Free PMC article. Preprint.
Designed Endocytosis-Triggering Proteins mediate Targeted Degradation.
Huang B, Abedi M, Ahn G, Coventry B, Sappington I, Wang R, Schlichthaerle T, Zhang JZ, Wang Y, Goreshnik I, Chiu CW, Chazin-Gray A, Chan S, Gerben S, Murray A, Wang S, O'Neill J, Yeh R, Misquith A, Wolf A, Tomasovic LM, Piraner DI, Gonzalez MJD, Bennett NR, Venkatesh P, Satoe D, Ahlrichs M, Dobbins C, Yang W, Wang X, Vafeados D, Mout R, Shivaei S, Cao L, Carter L, Stewart L, Spangler JB, Bernardes GJL, Roybal KT, Greisen P Jr, Li X, Bertozzi C, Baker D. Huang B, et al. Among authors: yang w. bioRxiv [Preprint]. 2023 Sep 20:2023.08.19.553321. doi: 10.1101/2023.08.19.553321. bioRxiv. 2023. PMID: 37781607 Free PMC article. Preprint.
Detection of antibodies neutralizing historical and emerging SARS-CoV-2 strains using a thermodynamically coupled de novo biosensor system.
Zhang JZ, Yeh HW, Walls AC, Wicky BIM, Sprouse K, VanBlargan LA, Treger R, Quijano-Rubio A, Pham MN, Kraft JC, Haydon IC, Yang W, DeWitt M, Chow C, Carter L, Wener MH, Stewart L, Veesler D, Diamond MS, Baker D. Zhang JZ, et al. Among authors: yang w. bioRxiv [Preprint]. 2021 Jun 22:2021.06.22.449355. doi: 10.1101/2021.06.22.449355. bioRxiv. 2021. Update in: Nat Biotechnol. 2022 Sep;40(9):1336-1340. doi: 10.1038/s41587-022-01280-8. PMID: 34189528 Free PMC article. Updated. Preprint.
Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies.
Edman NI, Redler RL, Phal A, Schlichthaerle T, Srivatsan SR, Etemadi A, An SJ, Favor A, Ehnes D, Li Z, Praetorius F, Gordon M, Yang W, Coventry B, Hicks DR, Cao L, Bethel N, Heine P, Murray A, Gerben S, Carter L, Miranda M, Negahdari B, Lee S, Trapnell C, Stewart L, Ekiert DC, Schlessinger J, Shendure J, Bhabha G, Ruohola-Baker H, Baker D. Edman NI, et al. Among authors: yang w. bioRxiv [Preprint]. 2023 Mar 15:2023.03.14.532666. doi: 10.1101/2023.03.14.532666. bioRxiv. 2023. Update in: Cell. 2024 Jul 11;187(14):3726-3740.e43. doi: 10.1016/j.cell.2024.05.025. PMID: 36993355 Free PMC article. Updated. Preprint.
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