Park S-Y - Search Results

1

Kinetics-based inference of environment-dependent microbial interactions and their dynamic variation.

Song H-S, Lee N-R, Kessell AK, McCullough HC, Park S-Y, Zhou K, Lee D-Y. Song H-S, et al. mSystems. 2024 May 16;9(5):e0130523. doi: 10.1128/msystems.01305-23. Epub 2024 Apr 29. mSystems. 2024. PMID: 38682902 Free PMC article.

2

Data-driven prediction models for forecasting multistep ahead profiles of mammalian cell culture toward bioprocess digital twins.

Park SY, Kim SJ, Park CH, Kim J, Lee DY. Park SY, et al. Biotechnol Bioeng. 2023 Sep;120(9):2494-2508. doi: 10.1002/bit.28405. Epub 2023 Apr 20. Biotechnol Bioeng. 2023. PMID: 37079452

3

Combined multivariate statistical and flux balance analyses uncover media bottlenecks to the growth and productivity of Chinese hamster ovary cell cultures.

Yeo HC, Park SY, Tan T, Ng SK, Lakshmanan M, Lee DY. Yeo HC, et al. Biotechnol Bioeng. 2022 Jul;119(7):1740-1754. doi: 10.1002/bit.28104. Epub 2022 Apr 25. Biotechnol Bioeng. 2022. PMID: 35435243

4

Debottlenecking and reformulating feed media for improved CHO cell growth and titer by data-driven and model-guided analyses.

Park SY, Choi DH, Song J, Park U, Cho H, Hong BH, Silberberg YR, Lee DY. Park SY, et al. Biotechnol J. 2023 Dec;18(12):e2300126. doi: 10.1002/biot.202300126. Epub 2023 Aug 27. Biotechnol J. 2023. PMID: 37605365

5

Genome-scale metabolic modeling and in silico analysis of opportunistic skin pathogen Cutibacterium acnes.

Kim SK, Lee M, Lee YQ, Lee HJ, Rho M, Kim Y, Seo JY, Youn SH, Hwang SJ, Kang NG, Lee CH, Park SY, Lee DY. Kim SK, et al. Front Cell Infect Microbiol. 2023 Jul 13;13:1099314. doi: 10.3389/fcimb.2023.1099314. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37520435 Free PMC article.

6

Exploring metabolic effects of dipeptide feed media on CHO cell cultures by in silico model-guided flux analysis.

Park SY, Song J, Choi DH, Park U, Cho H, Hong BH, Silberberg YR, Lee DY. Park SY, et al. Appl Microbiol Biotechnol. 2024 Dec;108(1):123. doi: 10.1007/s00253-023-12997-0. Epub 2024 Jan 16. Appl Microbiol Biotechnol. 2024. PMID: 38229404 Free PMC article.

7

Decoding cellular mechanism of recombinant adeno-associated virus (rAAV) and engineering host-cell factories toward intensified viral vector manufacturing.

Wang Y, Fu Q, Park SY, Lee YS, Park SY, Lee DY, Yoon S. Wang Y, et al. Biotechnol Adv. 2024 Mar-Apr;71:108322. doi: 10.1016/j.biotechadv.2024.108322. Epub 2024 Feb 7. Biotechnol Adv. 2024. PMID: 38336188 Review.

8

Driving towards digital biomanufacturing by CHO genome-scale models.

Park SY, Choi DH, Song J, Lakshmanan M, Richelle A, Yoon S, Kontoravdi C, Lewis NE, Lee DY. Park SY, et al. Trends Biotechnol. 2024 Sep;42(9):1192-1203. doi: 10.1016/j.tibtech.2024.03.001. Epub 2024 Mar 28. Trends Biotechnol. 2024. PMID: 38548556 Review.

9

Data-driven and model-guided systematic framework for media development in CHO cell culture.

Hong JK, Choi DH, Park SY, Silberberg YR, Shozui F, Nakamura E, Kayahara T, Lee DY. Hong JK, et al. Metab Eng. 2022 Sep;73:114-123. doi: 10.1016/j.ymben.2022.07.003. Epub 2022 Jul 4. Metab Eng. 2022. PMID: 35798249

10

Untargeted proteomics reveals upregulation of stress response pathways during CHO-based monoclonal antibody manufacturing process leading to disulfide bond reduction.

Park SY, Egan S, Cura AJ, Aron KL, Xu X, Zheng M, Borys M, Ghose S, Li Z, Lee K. Park SY, et al. MAbs. 2021 Jan-Dec;13(1):1963094. doi: 10.1080/19420862.2021.1963094. MAbs. 2021. PMID: 34424810 Free PMC article.

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