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Innate immune activation restricts priming and protective efficacy of the radiation-attenuated PfSPZ malaria vaccine.
Senkpeil L, Bhardwaj J, Little MR, Holla P, Upadhye A, Fusco EM, Swanson PA 2nd, Wiegand RE, Macklin MD, Bi K, Flynn BJ, Yamamoto A, Gaskin EL, Sather DN, Oblak AL, Simpson E, Gao H, Haining WN, Yates KB, Liu X, Murshedkar T, Richie TL, Sim BKL, Otieno K, Kariuki S, Xuei X, Liu Y, Polidoro RB, Hoffman SL, Oneko M, Steinhardt LC, Schmidt NW, Seder RA, Tran TM. Senkpeil L, et al. Among authors: macklin md. JCI Insight. 2024 Apr 30;9(11):e167408. doi: 10.1172/jci.insight.167408. JCI Insight. 2024. PMID: 38687615 Free PMC article. Clinical Trial.
Synergistic malaria vaccine combinations identified by systematic antigen screening.
Bustamante LY, Powell GT, Lin YC, Macklin MD, Cross N, Kemp A, Cawkill P, Sanderson T, Crosnier C, Muller-Sienerth N, Doumbo OK, Traore B, Crompton PD, Cicuta P, Tran TM, Wright GJ, Rayner JC. Bustamante LY, et al. Among authors: macklin md. Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):12045-12050. doi: 10.1073/pnas.1702944114. Epub 2017 Oct 23. Proc Natl Acad Sci U S A. 2017. PMID: 29078270 Free PMC article.
A phase I study of immunization using particle-mediated epidermal delivery of genes for gp100 and GM-CSF into uninvolved skin of melanoma patients.
Cassaday RD, Sondel PM, King DM, Macklin MD, Gan J, Warner TF, Zuleger CL, Bridges AJ, Schalch HG, Kim KM, Hank JA, Mahvi DM, Albertini MR. Cassaday RD, et al. Among authors: macklin md. Clin Cancer Res. 2007 Jan 15;13(2 Pt 1):540-9. doi: 10.1158/1078-0432.CCR-06-2039. Clin Cancer Res. 2007. PMID: 17255276 Clinical Trial.
32 results