Delwig A - Search Results

1

Context-Specific Stress Causes Compartmentalized SARM1 Activation and Local Degeneration in Cortical Neurons.

Hinz FI, Villegas CLM, Roberts JT, Yao H, Gaddam S, Delwig A, Green SA, Fredrickson C, Adrian M, Asuncion RR, Cheung TK, Hayne M, Hackos DH, Rose CM, Richmond D, Hoogenraad CC. Hinz FI, et al. Among authors: delwig a. J Neurosci. 2024 Jun 12;44(24):e2424232024. doi: 10.1523/JNEUROSCI.2424-23.2024. J Neurosci. 2024. PMID: 38692735 Free PMC article.

2

Discovery of Selective Inhibitors of Na_V1.7 Templated on Saxitoxin as Therapeutics for Pain.

Pajouhesh H, Delwig A, Beckley JT, Klas S, Monteleone D, Zhou X, Luu G, Du Bois J, Hunter JC, Mulcahy JV. Pajouhesh H, et al. Among authors: delwig a. ACS Med Chem Lett. 2022 Oct 18;13(11):1763-1768. doi: 10.1021/acsmedchemlett.2c00378. eCollection 2022 Nov 10. ACS Med Chem Lett. 2022. PMID: 36385936 Free PMC article.

3

ST-2560, a selective inhibitor of the Na_V1.7 sodium channel, affects nocifensive and cardiovascular reflexes in non-human primates.

Mulcahy JV, Beckley JT, Klas SD, Odink DA, Delwig A, Pajouhesh H, Monteleone D, Zhou X, Du Bois J, Yeomans DC, Luu G, Hunter JC. Mulcahy JV, et al. Among authors: delwig a. Br J Pharmacol. 2024 Sep;181(17):3160-3171. doi: 10.1111/bph.16398. Epub 2024 May 7. Br J Pharmacol. 2024. PMID: 38715413

4

Congenital Insensitivity to Pain: A Case Report With Corneal Esthesiometry and In Vivo Confocal Microscopy.

Keenan JD, Gonzales JA, Waxman SG, Delwig A. Keenan JD, et al. Among authors: delwig a. Cornea. 2021 Dec 1;40(12):1610-1613. doi: 10.1097/ICO.0000000000002650. Cornea. 2021. PMID: 34749381

5

Antinociceptive properties of an isoform-selective inhibitor of Nav1.7 derived from saxitoxin in mouse models of pain.

Beckley JT, Pajouhesh H, Luu G, Klas S, Delwig A, Monteleone D, Zhou X, Giuvelis D, Meng ID, Yeomans DC, Hunter JC, Mulcahy JV. Beckley JT, et al. Among authors: delwig a. Pain. 2021 Apr 1;162(4):1250-1261. doi: 10.1097/j.pain.0000000000002112. Pain. 2021. PMID: 33086288 Free PMC article.

6

Discovery of a selective, state-independent inhibitor of Na_V1.7 by modification of guanidinium toxins.

Pajouhesh H, Beckley JT, Delwig A, Hajare HS, Luu G, Monteleone D, Zhou X, Ligutti J, Amagasu S, Moyer BD, Yeomans DC, Du Bois J, Mulcahy JV. Pajouhesh H, et al. Among authors: delwig a. Sci Rep. 2020 Sep 9;10(1):14791. doi: 10.1038/s41598-020-71135-2. Sci Rep. 2020. PMID: 32908170 Free PMC article.

7

Challenges and Opportunities for Therapeutics Targeting the Voltage-Gated Sodium Channel Isoform Na_V1.7.

Mulcahy JV, Pajouhesh H, Beckley JT, Delwig A, Du Bois J, Hunter JC. Mulcahy JV, et al. Among authors: delwig a. J Med Chem. 2019 Oct 10;62(19):8695-8710. doi: 10.1021/acs.jmedchem.8b01906. Epub 2019 May 7. J Med Chem. 2019. PMID: 31012583 Free PMC article. Review.

8

Melanopsin expression in the cornea.

Delwig A, Chaney SY, Bertke AS, Verweij J, Quirce S, Larsen DD, Yang C, Buhr E, VAN Gelder R, Gallar J, Margolis T, Copenhagen DR. Delwig A, et al. Vis Neurosci. 2018 Jan;35:E004. doi: 10.1017/S0952523817000359. Vis Neurosci. 2018. PMID: 29905117 Free PMC article.

9

Retinofugal Projections from Melanopsin-Expressing Retinal Ganglion Cells Revealed by Intraocular Injections of Cre-Dependent Virus.

Delwig A, Larsen DD, Yasumura D, Yang CF, Shah NM, Copenhagen DR. Delwig A, et al. PLoS One. 2016 Feb 19;11(2):e0149501. doi: 10.1371/journal.pone.0149501. eCollection 2016. PLoS One. 2016. PMID: 26895233 Free PMC article.

10

Topical Valganciclovir for the Treatment of Hypertensive Anterior Uveitis.

Delwig A, Keenan JD, Margolis TP. Delwig A, et al. Cornea. 2015 Nov;34(11):1513-5. doi: 10.1097/ICO.0000000000000579. Cornea. 2015. PMID: 26356754 Review.

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