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18 results

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Page 1
Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomas.
Choi J, Ceribelli M, Phelan JD, Häupl B, Huang DW, Wright GW, Hsiao T, Morris V, Ciccarese F, Wang B, Corcoran S, Scheich S, Yu X, Xu W, Yang Y, Zhao H, Zhou J, Zhang G, Muppidi J, Inghirami GG, Oellerich T, Wilson WH, Thomas CJ, Staudt LM. Choi J, et al. Among authors: inghirami gg. Cancer Cell. 2024 May 13;42(5):833-849.e12. doi: 10.1016/j.ccell.2024.04.007. Epub 2024 May 2. Cancer Cell. 2024. PMID: 38701792
EZH2 inhibition enhances T cell immunotherapies by inducing lymphoma immunogenicity and improving T cell function.
Isshiki Y, Chen X, Teater M, Karagiannidis I, Nam H, Cai W, Meydan C, Xia M, Shen H, Gutierrez J, Easwar Kumar V, Carrasco SE, Ouseph MM, Yamshon S, Martin P, Griess O, Shema E, Porazzi P, Ruella M, Brentjens RJ, Inghirami G, Zappasodi R, Chadburn A, Melnick AM, Béguelin W. Isshiki Y, et al. Cancer Cell. 2025 Jan 13;43(1):49-68.e9. doi: 10.1016/j.ccell.2024.11.006. Epub 2024 Dec 5. Cancer Cell. 2025. PMID: 39642889
Mutability and hypermutation antagonize immunoglobulin codon optimality.
McGrath JJC, Park J, Troxell CA, Chervin JC, Li L, Kent JR, Changrob S, Fu Y, Huang M, Zheng NY, Wilbanks GD, Nelson SA, Sun J, Inghirami G, Madariaga MLL, Georgiou G, Wilson PC. McGrath JJC, et al. Mol Cell. 2024 Dec 12:S1097-2765(24)00988-2. doi: 10.1016/j.molcel.2024.11.033. Online ahead of print. Mol Cell. 2024. PMID: 39708804
Epithelial aPKC deficiency leads to stem cell loss preceding metaplasia in colorectal cancer initiation.
Kinoshita H, Martinez-Ordoñez A, Cid-Diaz T, Han Q, Duran A, Muta Y, Zhang X, Linares JF, Nakanishi Y, Kasashima H, Yashiro M, Maeda K, Albaladejo-Gonzalez A, Torres-Moreno D, García-Solano J, Conesa-Zamora P, Inghirami G, Diaz-Meco MT, Moscat J. Kinoshita H, et al. Dev Cell. 2024 Aug 5;59(15):1972-1987.e8. doi: 10.1016/j.devcel.2024.05.001. Epub 2024 May 29. Dev Cell. 2024. PMID: 38815584
Co-shared genomic alterations within tumors from patients with both myeloproliferative neoplasms and lymphoma.
Holst JM, Pedersen MB, Enemark MB, Hansen MC, Noerhave PR, Plesner TL, Frederiksen H, Moeller MB, Hamilton-Dutoit SJ, Noergaard P, Mortensen BK, Ommen HB, Stentoft J, Tam W, Ludvigsen M, Chan WC, Birkbak NJ, Inghirami G, D'Amore F. Holst JM, et al. Haematologica. 2024 Dec 1;109(12):4067-4072. doi: 10.3324/haematol.2023.283798. Haematologica. 2024. PMID: 39049601 Free PMC article. No abstract available.
Targeting CCR7-PI3Kγ overcomes resistance to tyrosine kinase inhibitors in ALK-rearranged lymphoma.
Mastini C, Campisi M, Patrucco E, Mura G, Ferreira A, Costa C, Ambrogio C, Germena G, Martinengo C, Peola S, Mota I, Vissio E, Molinaro L, Arigoni M, Olivero M, Calogero R, Prokoph N, Tabbò F, Shoji B, Brugieres L, Geoerger B, Turner SD, Cuesta-Mateos C, D'Aliberti D, Mologni L, Piazza R, Gambacorti-Passerini C, Inghirami GG, Chiono V, Kamm RD, Hirsch E, Koch R, Weinstock DM, Aster JC, Voena C, Chiarle R. Mastini C, et al. Among authors: inghirami gg. Sci Transl Med. 2023 Jun 28;15(702):eabo3826. doi: 10.1126/scitranslmed.abo3826. Epub 2023 Jun 28. Sci Transl Med. 2023. PMID: 37379367 Free PMC article.
Correction: Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma.
Prutsch N, Gurnhofer E, Suske T, Liang HC, Schlederer M, Roos S, Wu LC, Simonitsch-Klupp I, Alvarez-Hernandez A, Kornauth C, Leone DA, Svinka J, Eferl R, Limberger T, Aufinger A, Shirsath N, Wolf P, Hielscher T, Sternberg C, Aberger F, Schmoellerl J, Stoiber D, Strobl B, Jäger U, Staber PB, Grebien F, Moriggl R, Müller M, Inghirami GG, Sanda T, Look AT, Turner SD, Kenner L, Merkel O. Prutsch N, et al. Among authors: inghirami gg. Leukemia. 2020 Nov;34(11):3105. doi: 10.1038/s41375-020-0968-9. Leukemia. 2020. PMID: 32665700 Free PMC article.
18 results