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Tumor Infiltrating Effector Memory Antigen-Specific CD8+ T Cells Predict Response to Immune Checkpoint Therapy.
Principe N, Kidman J, Goh S, Tilsed CM, Fisher SA, Fear VS, Forbes CA, Zemek RM, Chopra A, Watson M, Dick IM, Boon L, Holt RA, Lake RA, Nowak AK, Lesterhuis WJ, McDonnell AM, Chee J. Principe N, et al. Among authors: lesterhuis wj. Front Immunol. 2020 Nov 12;11:584423. doi: 10.3389/fimmu.2020.584423. eCollection 2020. Front Immunol. 2020. PMID: 33262762 Free PMC article.
Comprehensive Testing of Chemotherapy and Immune Checkpoint Blockade in Preclinical Cancer Models Identifies Additive Combinations.
Principe N, Aston WJ, Hope DE, Tilsed CM, Fisher SA, Boon L, Dick IM, Chin WL, McDonnell AM, Nowak AK, Lake RA, Chee J, Lesterhuis WJ. Principe N, et al. Among authors: lesterhuis wj. Front Immunol. 2022 May 11;13:872295. doi: 10.3389/fimmu.2022.872295. eCollection 2022. Front Immunol. 2022. PMID: 35634282 Free PMC article.
CD4+ T cells drive an inflammatory, TNF-α/IFN-rich tumor microenvironment responsive to chemotherapy.
Tilsed CM, Principe N, Kidman J, Chin WL, Orozco Morales ML, Zemek RM, Chee J, Islam R, Fear VS, Forbes C, Aston WJ, Jansen M, Chopra A, Lassmann T, Nowak AK, Fisher SA, Lake RA, Lesterhuis WJ. Tilsed CM, et al. Among authors: lesterhuis wj. Cell Rep. 2022 Dec 27;41(13):111874. doi: 10.1016/j.celrep.2022.111874. Cell Rep. 2022. PMID: 36577370 Free article.
A surgically optimized intraoperative poly(I:C)-releasing hydrogel prevents cancer recurrence.
Rwandamuriye FX, Evans CW, Wylie B, Norret M, Vitali B, Ho D, Nguyen D, Roper EA, Wang T, Hepburn MS, Sanderson RW, Pfirrmann M, Fear VS, Forbes CA, Wyatt K, Ryan AL, Johns TG, Phillips MB, Hodder R, Leslie C, Kennedy BF, Zemek RM, Iyer KS, Lesterhuis WJ. Rwandamuriye FX, et al. Among authors: lesterhuis wj. Cell Rep Med. 2023 Jul 18;4(7):101113. doi: 10.1016/j.xcrm.2023.101113. Cell Rep Med. 2023. PMID: 37467718 Free PMC article.
83 results