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Attitudes toward genetic testing, family planning and preimplantation genetic testing in families with a germline CDKN2A pathogenic variant.
Onnekink AM, Klatte DCF, van Hooft JE, van den Berg SH, van der Zwaan SMS, van Doorn R, Hinnen SCH, Potjer TP, Bleiker EMA, van Leerdam ME. Onnekink AM, et al. Among authors: van den berg sh, van hooft je, van doorn r, van der zwaan sms, van leerdam me. Fam Cancer. 2024 Aug;23(3):255-265. doi: 10.1007/s10689-024-00401-3. Epub 2024 Jun 1. Fam Cancer. 2024. PMID: 38822936 Free PMC article.
The global leadership into malnutrition criteria reveals a high percentage of malnutrition which influences overall survival in patients with gastroenteropancreatic neuroendocrine tumours.
Clement DSVM, van Leerdam ME, Tesselaar MET, Cananea E, Martin W, Weickert MO, Sarker D, Ramage JK, Srirajaskanthan R. Clement DSVM, et al. Among authors: van leerdam me. J Neuroendocrinol. 2024 Apr;36(4):e13376. doi: 10.1111/jne.13376. Epub 2024 Feb 22. J Neuroendocrinol. 2024. PMID: 38389192
Germline variant affecting p53β isoforms predisposes to familial cancer.
Schubert SA, Ruano D, Joruiz SM, Stroosma J, Glavak N, Montali A, Pinto LM, Rodríguez-Girondo M, Barge-Schaapveld DQCM, Nielsen M, van Nesselrooij BPM, Mensenkamp AR, van Leerdam ME, Sharp TH, Morreau H, Bourdon JC, de Miranda NFCC, van Wezel T. Schubert SA, et al. Among authors: van leerdam me. Nat Commun. 2024 Sep 18;15(1):8208. doi: 10.1038/s41467-024-52551-8. Nat Commun. 2024. PMID: 39294166 Free PMC article.
Neoadjuvant Immunotherapy in Locally Advanced Mismatch Repair-Deficient Colon Cancer.
Chalabi M, Verschoor YL, Tan PB, Balduzzi S, Van Lent AU, Grootscholten C, Dokter S, Büller NV, Grotenhuis BA, Kuhlmann K, Burger JW, Huibregtse IL, Aukema TS, Hendriks ER, Oosterling SJ, Snaebjornsson P, Voest EE, Wessels LF, Beets-Tan RG, Van Leerdam ME, Schumacher TN, van den Berg JG, Beets GL, Haanen JB. Chalabi M, et al. Among authors: van lent au, van leerdam me, van den berg jg. N Engl J Med. 2024 Jun 6;390(21):1949-1958. doi: 10.1056/NEJMoa2400634. N Engl J Med. 2024. PMID: 38838311 Clinical Trial.
Individuals with Lynch syndrome have similar survival as the general population, but lower than family members without Lynch syndrome.
Karpati D, Nielsen M, Wagner A, Bajwa-Ten Broeke SW, Bleeker FE, van Leerdam ME; Netherlands Foundation for Detection of Hereditary Tumours Collaborative Investigators. Karpati D, et al. Among authors: van leerdam me. Gastroenterology. 2025 Jan 10:S0016-5085(25)00040-X. doi: 10.1053/j.gastro.2024.12.032. Online ahead of print. Gastroenterology. 2025. PMID: 39800080 No abstract available.
Risk of cancer and reoperation after ileorectal anastomosis and ileal pouch-anal anastomosis in familial adenomatous polyposis.
Bouchiba H, Aelvoet AS, Pellisé M, Bastiaansen BAJ, van Leerdam ME, Langers AMJ, Balaguer F, Miedema TN, Anele CC, Daca-Alvarez M, Bossuyt PMM, Ricciardiello L, Jover R, Hompes R, Karstensen JG, Latchford A, Dekker E; European FAP Consortium. Bouchiba H, et al. Among authors: van leerdam me. Am J Gastroenterol. 2024 Dec 31. doi: 10.14309/ajg.0000000000003273. Online ahead of print. Am J Gastroenterol. 2024. PMID: 39787348
High Prevalence of Sarcopenia in Patients with Newly Diagnosed Gastroenteropancreatic Neuroendocrine Tumours (GEP-NETs), but No Association with the Risk of Surgical Complications.
Clement DSVM, van Leerdam ME, Tesselaar MET, Srinivasan P, Menon K, Kuhlmann K, den Hartog A, Giovos G, Weickert MO, Srirajaskanthan R. Clement DSVM, et al. Among authors: van leerdam me. Nutrients. 2024 Nov 5;16(22):3790. doi: 10.3390/nu16223790. Nutrients. 2024. PMID: 39599579 Free PMC article.
286 results