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Page 1
CYpHER: Catalytic extracellular targeted protein degradation with high potency and durable effect.
Crook ZR, Sevilla GP, Young P, Girard EJ, Phi TD, Howard M, Price J, Olson JM, Nairn NW. Crook ZR, et al. Among authors: sevilla gp. bioRxiv [Preprint]. 2024 Apr 23:2024.02.21.581471. doi: 10.1101/2024.02.21.581471. bioRxiv. 2024. Update in: Nat Commun. 2024 Oct 9;15(1):8731. doi: 10.1038/s41467-024-52975-2. PMID: 38712232 Free PMC article. Updated. Preprint.
A TfR-Binding Cystine-Dense Peptide Promotes Blood-Brain Barrier Penetration of Bioactive Molecules.
Crook ZR, Girard E, Sevilla GP, Merrill M, Friend D, Rupert PB, Pakiam F, Nguyen E, Yin C, Ruff RO, Hopping G, Strand AD, Finton KAK, Coxon M, Mhyre AJ, Strong RK, Olson JM. Crook ZR, et al. Among authors: sevilla gp. J Mol Biol. 2020 Jun 26;432(14):3989-4009. doi: 10.1016/j.jmb.2020.04.002. Epub 2020 Apr 15. J Mol Biol. 2020. PMID: 32304700 Free PMC article.
Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager.
Crook ZR, Girard EJ, Sevilla GP, Brusniak MY, Rupert PB, Friend DJ, Gewe MM, Clarke M, Lin I, Ruff R, Pakiam F, Phi TD, Bandaranayake A, Correnti CE, Mhyre AJ, Nairn NW, Strong RK, Olson JM. Crook ZR, et al. Among authors: sevilla gp. Sci Transl Med. 2022 May 18;14(645):eabn0402. doi: 10.1126/scitranslmed.abn0402. Epub 2022 May 18. Sci Transl Med. 2022. PMID: 35584229 Free PMC article.
Genetic diversity of the HLA system in human populations from the Sierra (Andean), Oriente (Amazonian) and Costa (Coastal) regions of Ecuador.
Galarza JM, Barquera R, Álvarez AMT, Hernández Zaragoza DI, Sevilla GP, Tamayo A, Pérez M, Dávila D, Birnberg L, Alonzo VA, Krause J, Grijalva M. Galarza JM, et al. Among authors: sevilla gp. Hum Immunol. 2018 Sep;79(9):639-650. doi: 10.1016/j.humimm.2018.06.004. Epub 2018 Jun 13. Hum Immunol. 2018. PMID: 29908213