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Engineered CRISPR-Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing.
Kleinstiver BP, Sousa AA, Walton RT, Tak YE, Hsu JY, Clement K, Welch MM, Horng JE, Malagon-Lopez J, Scarfò I, Maus MV, Pinello L, Aryee MJ, Joung JK. Kleinstiver BP, et al. Among authors: hsu jy. Nat Biotechnol. 2019 Mar;37(3):276-282. doi: 10.1038/s41587-018-0011-0. Epub 2019 Feb 11. Nat Biotechnol. 2019. PMID: 30742127 Free PMC article.
Response to "Unexpected mutations after CRISPR-Cas9 editing in vivo".
Lareau CA, Clement K, Hsu JY, Pattanayak V, Joung JK, Aryee MJ, Pinello L. Lareau CA, et al. Among authors: hsu jy. Nat Methods. 2018 Apr;15(4):238-239. doi: 10.1038/nmeth.4541. Epub 2018 Mar 30. Nat Methods. 2018. PMID: 29600992 Free PMC article. No abstract available.
477 results