Ganguly D - Search Results

1

Exploring the Structural Attributes of Yoda1 for the Development of New-Generation Piezo1 Agonist Yaddle1 as a Vaccine Adjuvant Targeting Optimal T Cell Activation.

Goon S, Shiu Chen Liu C, Ghosh Dastidar U, Paul B, Mukherjee S, Sarkar HS, Desai M, Jana R, Pal S, Sreedevi NV, Ganguly D, Talukdar A. Goon S, et al. Among authors: ganguly d. J Med Chem. 2024 May 23;67(10):8225-8246. doi: 10.1021/acs.jmedchem.4c00322. Epub 2024 May 8. J Med Chem. 2024. PMID: 38716967

2

Design and development of benzoxazole derivatives with toll-like receptor 9 antagonism.

Roy S, Mukherjee A, Paul B, Rahaman O, Roy S, Maithri G, Ramya B, Pal S, Ganguly D, Talukdar A. Roy S, et al. Among authors: ganguly d. Eur J Med Chem. 2017 Jul 7;134:334-347. doi: 10.1016/j.ejmech.2017.03.086. Epub 2017 Apr 5. Eur J Med Chem. 2017. PMID: 28437629

3

Cutting Edge: Piezo1 Mechanosensors Optimize Human T Cell Activation.

Liu CSC, Raychaudhuri D, Paul B, Chakrabarty Y, Ghosh AR, Rahaman O, Talukdar A, Ganguly D. Liu CSC, et al. Among authors: ganguly d. J Immunol. 2018 Feb 15;200(4):1255-1260. doi: 10.4049/jimmunol.1701118. Epub 2018 Jan 12. J Immunol. 2018. PMID: 29330322

4

Activity-guided development of potent and selective toll-like receptor 9 antagonists.

Paul B, Rahaman O, Roy S, Pal S, Satish S, Mukherjee A, Ghosh AR, Raychaudhuri D, Bhattacharya R, Goon S, Ganguly D, Talukdar A. Paul B, et al. Among authors: ganguly d. Eur J Med Chem. 2018 Nov 5;159:187-205. doi: 10.1016/j.ejmech.2018.09.058. Epub 2018 Sep 26. Eur J Med Chem. 2018. PMID: 30292896

5

A Chemical Switch for Transforming a Purine Agonist for Toll-like Receptor 7 to a Clinically Relevant Antagonist.

Mukherjee A, Raychaudhuri D, Sinha BP, Kundu B, Mitra M, Paul B, Bandopadhyay P, Ganguly D, Talukdar A. Mukherjee A, et al. Among authors: ganguly d. J Med Chem. 2020 May 14;63(9):4776-4789. doi: 10.1021/acs.jmedchem.0c00011. Epub 2020 May 4. J Med Chem. 2020. PMID: 32302115

6

Synthesis and characterization of new potent TLR7 antagonists based on analysis of the binding mode using biomolecular simulations.

Pal S, Paul B, Bandopadhyay P, Preethy N, Sarkar D, Rahaman O, Goon S, Roy S, Ganguly D, Talukdar A. Pal S, et al. Among authors: ganguly d. Eur J Med Chem. 2021 Jan 15;210:112978. doi: 10.1016/j.ejmech.2020.112978. Epub 2020 Oct 31. Eur J Med Chem. 2021. PMID: 33189437

7

Structural Evolution and Translational Potential for Agonists and Antagonists of Endosomal Toll-like Receptors.

Talukdar A, Ganguly D, Roy S, Das N, Sarkar D. Talukdar A, et al. Among authors: ganguly d. J Med Chem. 2021 Jun 24;64(12):8010-8041. doi: 10.1021/acs.jmedchem.1c00300. Epub 2021 Jun 9. J Med Chem. 2021. PMID: 34107682

8

Systematic Optimization of Potent and Orally Bioavailable Purine Scaffold as a Dual Inhibitor of Toll-Like Receptors 7 and 9.

Kundu B, Raychaudhuri D, Mukherjee A, Sinha BP, Sarkar D, Bandopadhyay P, Pal S, Das N, Dey D, Ramarao K, Nagireddy K, Ganguly D, Talukdar A. Kundu B, et al. Among authors: ganguly d. J Med Chem. 2021 Jul 8;64(13):9279-9301. doi: 10.1021/acs.jmedchem.1c00532. Epub 2021 Jun 18. J Med Chem. 2021. PMID: 34142551

9

Integration of Ligand-Based and Structure-Based Methods for the Design of Small-Molecule TLR7 Antagonists.

Pal S, Ghosh Dastidar U, Ghosh T, Ganguly D, Talukdar A. Pal S, et al. Among authors: ganguly d. Molecules. 2022 Jun 23;27(13):4026. doi: 10.3390/molecules27134026. Molecules. 2022. PMID: 35807273 Free PMC article.

10

Development, Optimization, and In Vivo Validation of New Imidazopyridine Chemotypes as Dual TLR7/TLR9 Antagonists through Activity-Directed Sequential Incorporation of Relevant Structural Subunits.

Das N, Bandopadhyay P, Roy S, Sinha BP, Dastidar UG, Rahaman O, Pal S, Ganguly D, Talukdar A. Das N, et al. Among authors: ganguly d. J Med Chem. 2022 Sep 8;65(17):11607-11632. doi: 10.1021/acs.jmedchem.2c00386. Epub 2022 Aug 12. J Med Chem. 2022. PMID: 35959635

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