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Automated synthesis of (R)-[18 F]MH.MZ on the iPhase Flexlab reaction platform.
Rosenberg AJ, Cheung YY, Liu F, Peterson TE, Silverman J, Considine CM, Claassen DO. Rosenberg AJ, et al. Among authors: cheung yy. J Labelled Comp Radiopharm. 2022 Jun 30;65(8):223-229. doi: 10.1002/jlcr.3975. Epub 2022 May 6. J Labelled Comp Radiopharm. 2022. PMID: 35491085 Free PMC article.
Facile synthesis of SSR180575 and discovery of 7-chloro-N,N,5-trimethyl-4-oxo-3(6-[(18)F]fluoropyridin-2-yl)-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide, a potent pyridazinoindole ligand for PET imaging of TSPO in cancer.
Cheung YY, Nickels ML, Tang D, Buck JR, Manning HC. Cheung YY, et al. Bioorg Med Chem Lett. 2014 Sep 15;24(18):4466-4471. doi: 10.1016/j.bmcl.2014.07.091. Epub 2014 Aug 8. Bioorg Med Chem Lett. 2014. PMID: 25172419 Free PMC article.
Fully automated dual-run manufacturing of [11C]PIB on FASTlab.
Nair M, Cheung YY, Liu F, Koran ME, Rosenberg AJ. Nair M, et al. Among authors: cheung yy. Nucl Med Biol. 2024 Jan-Feb;128-129:108873. doi: 10.1016/j.nucmedbio.2023.108873. Epub 2023 Dec 25. Nucl Med Biol. 2024. PMID: 38154168 Free PMC article.
Discovery of a series of 2-phenyl-N-(2-(pyrrolidin-1-yl)phenyl)acetamides as novel molecular switches that modulate modes of K(v)7.2 (KCNQ2) channel pharmacology: identification of (S)-2-phenyl-N-(2-(pyrrolidin-1-yl)phenyl)butanamide (ML252) as a potent, brain penetrant K(v)7.2 channel inhibitor.
Cheung YY, Yu H, Xu K, Zou B, Wu M, McManus OB, Li M, Lindsley CW, Hopkins CR. Cheung YY, et al. J Med Chem. 2012 Aug 9;55(15):6975-9. doi: 10.1021/jm300700v. Epub 2012 Jul 26. J Med Chem. 2012. PMID: 22793372 Free PMC article.
86 results