Talbot K - Search Results

1

An ALS-associated mutation dysregulates microglia-derived extracellular microRNAs in a sex-specific manner.

Christoforidou E, Moody L, Joilin G, Simoes FA, Gordon D, Talbot K, Hafezparast M. Christoforidou E, et al. Among authors: talbot k. Dis Model Mech. 2024 May 1;17(5):dmm050638. doi: 10.1242/dmm.050638. Epub 2024 May 29. Dis Model Mech. 2024. PMID: 38721655 Free PMC article.

2

TARDBP pathogenic mutations increase cytoplasmic translocation of TDP-43 and cause reduction of endoplasmic reticulum Ca²⁺ signaling in motor neurons.

Mutihac R, Alegre-Abarrategui J, Gordon D, Farrimond L, Yamasaki-Mann M, Talbot K, Wade-Martins R. Mutihac R, et al. Among authors: talbot k. Neurobiol Dis. 2015 Mar;75:64-77. doi: 10.1016/j.nbd.2014.12.010. Epub 2014 Dec 17. Neurobiol Dis. 2015. PMID: 25526708

3

Single-copy expression of an amyotrophic lateral sclerosis-linked TDP-43 mutation (M337V) in BAC transgenic mice leads to altered stress granule dynamics and progressive motor dysfunction.

Gordon D, Dafinca R, Scaber J, Alegre-Abarrategui J, Farrimond L, Scott C, Biggs D, Kent L, Oliver PL, Davies B, Ansorge O, Wade-Martins R, Talbot K. Gordon D, et al. Among authors: talbot k. Neurobiol Dis. 2019 Jan;121:148-162. doi: 10.1016/j.nbd.2018.09.024. Epub 2018 Oct 2. Neurobiol Dis. 2019. PMID: 30290270 Free article.

4

Neuronal over-expression of Oxr1 is protective against ALS-associated mutant TDP-43 mislocalisation in motor neurons and neuromuscular defects in vivo.

Williamson MG, Finelli MJ, Sleigh JN, Reddington A, Gordon D, Talbot K, Davies KE, Oliver PL. Williamson MG, et al. Among authors: talbot k. Hum Mol Genet. 2019 Nov 1;28(21):3584-3599. doi: 10.1093/hmg/ddz190. Hum Mol Genet. 2019. PMID: 31642482 Free PMC article.

5

Mice Carrying ALS Mutant TDP-43, but Not Mutant FUS, Display In Vivo Defects in Axonal Transport of Signaling Endosomes.

Sleigh JN, Tosolini AP, Gordon D, Devoy A, Fratta P, Fisher EMC, Talbot K, Schiavo G. Sleigh JN, et al. Among authors: talbot k. Cell Rep. 2020 Mar 17;30(11):3655-3662.e2. doi: 10.1016/j.celrep.2020.02.078. Cell Rep. 2020. PMID: 32187538 Free PMC article.

6

Identification of a potential non-coding RNA biomarker signature for amyotrophic lateral sclerosis.

Joilin G, Gray E, Thompson AG, Bobeva Y, Talbot K, Weishaupt J, Ludolph A, Malaspina A, Leigh PN, Newbury SF, Turner MR, Hafezparast M. Joilin G, et al. Among authors: talbot k. Brain Commun. 2020;2(1):fcaa053. doi: 10.1093/braincomms/fcaa053. Epub 2020 Jun 17. Brain Commun. 2020. PMID: 32613197 Free PMC article.

7

An ALS-linked mutation in TDP-43 disrupts normal protein interactions in the motor neuron response to oxidative stress.

Feneberg E, Gordon D, Thompson AG, Finelli MJ, Dafinca R, Candalija A, Charles PD, Mäger I, Wood MJ, Fischer R, Kessler BM, Gray E, Turner MR, Talbot K. Feneberg E, et al. Among authors: talbot k. Neurobiol Dis. 2020 Oct;144:105050. doi: 10.1016/j.nbd.2020.105050. Epub 2020 Aug 13. Neurobiol Dis. 2020. PMID: 32800996 Free article.

8

Targeting phosphoglycerate kinase 1 with terazosin improves motor neuron phenotypes in multiple models of amyotrophic lateral sclerosis.

Chaytow H, Carroll E, Gordon D, Huang YT, van der Hoorn D, Smith HL, Becker T, Becker CG, Faller KME, Talbot K, Gillingwater TH. Chaytow H, et al. Among authors: talbot k. EBioMedicine. 2022 Sep;83:104202. doi: 10.1016/j.ebiom.2022.104202. Epub 2022 Aug 11. EBioMedicine. 2022. PMID: 35963713 Free PMC article.

9

Stress granule assembly in vivo is deficient in the CNS of mutant TDP-43 ALS mice.

Dubinski A, Gagné M, Peyrard S, Gordon D, Talbot K, Vande Velde C. Dubinski A, et al. Among authors: talbot k. Hum Mol Genet. 2023 Jan 6;32(2):319-332. doi: 10.1093/hmg/ddac206. Hum Mol Genet. 2023. PMID: 35994036 Free PMC article.

10

Profiling non-coding RNA expression in cerebrospinal fluid of amyotrophic lateral sclerosis patients.

Joilin G, Gray E, Thompson AG, Talbot K, Leigh PN, Newbury SF, Turner MR, Hafezparast M. Joilin G, et al. Among authors: talbot k. Ann Med. 2022 Dec;54(1):3069-3078. doi: 10.1080/07853890.2022.2138530. Ann Med. 2022. PMID: 36314539 Free PMC article.

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