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Page 1
Secreted Apoe rewires melanoma cell state vulnerability to ferroptosis.
More S, Bonnereau J, Wouters D, Spotbeen X, Karras P, Rizzollo F, Killian T, Venken T, Naulaerts S, Vervoort E, Ganne M, Nittner D, Verhoeven J, Bechter O, Bosisio F, Lambrechts D, Sifrim A, Stockwell BR, Swinnen JV, Marine JC, Agostinis P. More S, et al. Among authors: naulaerts s. Sci Adv. 2024 Oct 18;10(42):eadp6164. doi: 10.1126/sciadv.adp6164. Epub 2024 Oct 16. Sci Adv. 2024. PMID: 39413195 Free article.
Trial watch: anticancer vaccination with dendritic cells.
Borges F, Laureano RS, Vanmeerbeek I, Sprooten J, Demeulenaere O, Govaerts J, Kinget L, Saraswat S, Beuselinck B, De Vleeschouwer S, Clement P, De Smet F, Sorg RV, Datsi A, Vigneron N, Naulaerts S, Garg AD. Borges F, et al. Among authors: naulaerts s. Oncoimmunology. 2024 Oct 9;13(1):2412876. doi: 10.1080/2162402X.2024.2412876. eCollection 2024. Oncoimmunology. 2024. PMID: 39398476 Free PMC article. Review.
Targeting conserved TIM3+VISTA+ tumor-associated macrophages overcomes resistance to cancer immunotherapy.
Vanmeerbeek I, Naulaerts S, Sprooten J, Laureano RS, Govaerts J, Trotta R, Pretto S, Zhao S, Cafarello ST, Verelst J, Jacquemyn M, Pociupany M, Boon L, Schlenner SM, Tejpar S, Daelemans D, Mazzone M, Garg AD. Vanmeerbeek I, et al. Among authors: naulaerts s. Sci Adv. 2024 Jul 19;10(29):eadm8660. doi: 10.1126/sciadv.adm8660. Epub 2024 Jul 19. Sci Adv. 2024. PMID: 39028818 Free PMC article.
Author Correction: A spatial architecture-embedding HLA signature to predict clinical response to immunotherapy in renal cell carcinoma.
Kinget L, Naulaerts S, Govaerts J, Vanmeerbeek I, Sprooten J, Laureano RS, Dubroja N, Shankar G, Bosisio FM, Roussel E, Verbiest A, Finotello F, Ausserhofer M, Lambrechts D, Boeckx B, Wozniak A, Boon L, Kerkhofs J, Zucman-Rossi J, Albersen M, Baldewijns M, Beuselinck B, Garg AD. Kinget L, et al. Among authors: naulaerts s. Nat Med. 2024 Aug;30(8):2375-2376. doi: 10.1038/s41591-024-03174-5. Nat Med. 2024. PMID: 39009782 No abstract available.
Nucleotide metabolism in cancer cells fuels a UDP-driven macrophage cross-talk, promoting immunosuppression and immunotherapy resistance.
Scolaro T, Manco M, Pecqueux M, Amorim R, Trotta R, Van Acker HH, Van Haele M, Shirgaonkar N, Naulaerts S, Daniluk J, Prenen F, Varamo C, Ponti D, Doglioni G, Ferreira Campos AM, Fernandez Garcia J, Radenkovic S, Rouhi P, Beatovic A, Wang L, Wang Y, Tzoumpa A, Antoranz A, Sargsian A, Di Matteo M, Berardi E, Goveia J, Ghesquière B, Roskams T, Soenen S, Voets T, Manshian B, Fendt SM, Carmeliet P, Garg AD, DasGupta R, Topal B, Mazzone M. Scolaro T, et al. Among authors: naulaerts s. Nat Cancer. 2024 Aug;5(8):1206-1226. doi: 10.1038/s43018-024-00771-8. Epub 2024 Jun 6. Nat Cancer. 2024. PMID: 38844817 Free PMC article.
A spatial architecture-embedding HLA signature to predict clinical response to immunotherapy in renal cell carcinoma.
Kinget L, Naulaerts S, Govaerts J, Vanmeerbeek I, Sprooten J, Laureano RS, Dubroja N, Shankar G, Bosisio FM, Roussel E, Verbiest A, Finotello F, Ausserhofer M, Lambrechts D, Boeckx B, Wozniak A, Boon L, Kerkhofs J, Zucman-Rossi J, Albersen M, Baldewijns M, Beuselinck B, Garg AD. Kinget L, et al. Among authors: naulaerts s. Nat Med. 2024 Jun;30(6):1667-1679. doi: 10.1038/s41591-024-02978-9. Epub 2024 May 21. Nat Med. 2024. PMID: 38773341
Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacy.
Wang C, Zeng Q, Gül ZM, Wang S, Pick R, Cheng P, Bill R, Wu Y, Naulaerts S, Barnoud C, Hsueh PC, Moller SH, Cenerenti M, Sun M, Su Z, Jemelin S, Petrenko V, Dibner C, Hugues S, Jandus C, Li Z, Michielin O, Ho PC, Garg AD, Simonetta F, Pittet MJ, Scheiermann C. Wang C, et al. Among authors: naulaerts s. Cell. 2024 May 23;187(11):2690-2702.e17. doi: 10.1016/j.cell.2024.04.015. Epub 2024 May 8. Cell. 2024. PMID: 38723627 Free article.
Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells.
Sprooten J, Vanmeerbeek I, Datsi A, Govaerts J, Naulaerts S, Laureano RS, Borràs DM, Calvet A, Malviya V, Kuballa M, Felsberg J, Sabel MC, Rapp M, Knobbe-Thomsen C, Liu P, Zhao L, Kepp O, Boon L, Tejpar S, Borst J, Kroemer G, Schlenner S, De Vleeschouwer S, Sorg RV, Garg AD. Sprooten J, et al. Among authors: naulaerts s. Cell Rep Med. 2024 Jan 16;5(1):101377. doi: 10.1016/j.xcrm.2023.101377. Cell Rep Med. 2024. PMID: 38232703 Free PMC article.
Single cell dynamics of tumor specificity vs bystander activity in CD8+ T cells define the diverse immune landscapes in colorectal cancer.
Borràs DM, Verbandt S, Ausserhofer M, Sturm G, Lim J, Verge GA, Vanmeerbeek I, Laureano RS, Govaerts J, Sprooten J, Hong Y, Wall R, De Hertogh G, Sagaert X, Bislenghi G, D'Hoore A, Wolthuis A, Finotello F, Park WY, Naulaerts S, Tejpar S, Garg AD. Borràs DM, et al. Among authors: naulaerts s. Cell Discov. 2023 Nov 15;9(1):114. doi: 10.1038/s41421-023-00605-4. Cell Discov. 2023. PMID: 37968259 Free PMC article.
32 results